The Ledger, every show
Every statement that passed quotation and attribution checks, across all 44 shows. Pick shows below, then mix any filter with any other.
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every show 44 of 44
Huberman: Most men 40+ should probably take 2.5 to 5mg Tadalafil
“The basic takeaway is that most every male, 40 and older, should probably be taking somewhere between 2.5 and five milligrams of Tadalafil, not necessarily for erectile function, although it will augment that as well, but to lower blood pressure and to improve…”
Huberman: GLP-1 proved people become fat because they eat too much
“It also, by the way, shut down the debate as to why people are fat. It's because they eat too much.”
Huberman: NIH grants often fund already-completed research rather than bold science
“Much of the work that's funded by NIH Here's the dirty secret is already completed because they tend to fund things that are very certain to be completed. And so people put forward grants based on work and preliminary data showing I can do this and it's alread…”
Huberman: Hair loss drugs finasteride and dutasteride can cause permanent sexual dysfunction
“There's this whole thing about people taking finasteride and dutasteride men to keep their hair and getting permanent sexual dysfunction, right? Permanent sexual dysfunction. Some of them killing themselves as a consequence of this.”
Huberman: U.S. Academic Science Should Replace PI Labs With Mission-Driven Incubators
“I think the independent investigator model of science in this country, where it's the Huberman lab, or it's the whatever lab named after the PI, I think that's a flawed model. This is gonna really upset some people. There should be labs named after a particula…”
Huberman: Most NIH-funded research is completed before grant approval
“Much of the work that's funded by NIH. Here's the dirty secret is already completed because they tend to fund things that are very certain to be completed. And so people put forward grants based on work and preliminary data showing I can do this. And it's alre…”
Academic science should replace PI labs with mission-focused labs
“I think that the independent investigator model of science in this country, where it's the Huberman lab, or it's the whatever lab named after the PI, I think that's a flawed model. This is gonna really upset some people. There should be labs named after a part…”
Huberman: People should not inject peptides labeled for research purposes only
“I do not think anyone should inject peptides that are labeled as for research purposes only because even if it says 99% purity, the one percent is likely to be something called LPS, lipopolysaccharide, which can cause inflammation. It's not a good thing to be …”
Huberman: Retatrutide will become a trillion-dollar drug
“This is going to be a trillion dollar drug, trillion dollar, but people are already taking it.”
Huberman: Predisposed Young Males Risk Irreversible Cannabis-Induced Psychosis
“There is a population of people, especially young males who have a predisposition to schizophrenia or bipolar, meaning they have a first relative with those conditions. That are very high risk for cannabis-induced psychosis, some of which doesn't reverse, whic…”
Huberman: Congress is considering a 40% cut to NIH research budget
“There is an upcoming vote in Congress in September, I believe, and it's on the table to cut the overall budget for research for NIH by 40%, four to zero.”
Huberman: Trump administration proposed capping university indirect costs at 15%
“Earlier this year, the Trump administration said, We're cutting that to 15% across the board for all universities”
Huberman: Stem cells are not yet ready for clinical use
“No, they're not ready for clinical use yet, and the United States has been very careful about things like this”
Huberman: Data shows microdosing psilocybin lacks major effects on depression or PTSD
“The data on microdosing psilocybin Are basically clear that it's not known to have any major effect on major depression or some of the other things that psilocybin is being tested for clinically including major depression, PTSD, et cetera.”
Huberman: MDMA will ultimately receive FDA approval for PTSD
“So I think ultimately it will be approved.”
Huberman: Funded research grants often fail the critical laboratory deletion test
“I sat on study section for a long time, and I can tell you there were clusters of grants that didn't solve what we call, what good labs call, the deletion test. If this laboratory didn't exist, would it change the direction of science? You have to pass the del…”
Congress is considering a 40 percent budget cut to the NIH
“There is an upcoming vote in Congress in September, I believe, and it's on the table to cut the overall budget for research for NIH by 40%, four zero.”
Huberman: Microdosing psilocybin has no major therapeutic effect on depression
“The data on micro dosing psilocybin are basically clear that it's not known to have any major effect on major depression. Or some of the other things that psilocybin is being tested for clinically including major depression, PTSD, et cetera.”
Huberman: Neuralink will solve paralysis
“I fully believe that Neuralink is going to solve paralysis. I really do. I'm not saying that cause we're on exits. I know the head neurosurgeon there, they're well on their way.”
Huberman: BPC-157 is very hard to test for in doping control
“You're going to see peptides like BPC one, five, seven, I believe is banned. But that's a naturally occurring gut peptide. Very hard to test for because you have tons of it circulating and the synthetic versions may or may not differ from that version as much …”
Huberman: Growth hormone boosts short-term vitality but accelerates aging
“This is the thing that people don't realize that there's always a dynamic tension between the things that give you vitality and the things that extend your life. For instance, if you take growth hormone, you'll feel more vital. You'll gain muscle more easily, …”
Huberman: Slashing indirect research costs will disproportionately hurt unendowed public universities
“I just personally, it's my view, this is my personal view, is that a severe cut to the indirects, while on the face of it might sound good, that's going to disproportionately Hurt the public schools without large endowments, okay, because they don't have money…”
Huberman: Peptides should not be relegated to gray-market gym testing
“It's my opinion that every single peptide, not just GLP-I, every single peptide shouldn't be getting tested in the gray market of, like, gyms and, like, biohacking. That's, frankly, that's bullshit.”
Huberman: Properly dosed MDMA yields 60% to 70% PTSD remission rates
“The remission rates on PTSD, by the way, from Properly dosed and spaced MDMA is remarkable. Up to somewhere between 60 and 70% remission rates on PTSD.”
Huberman: Using Close Peer Juries for Grant Evaluation Is Flawed
“The idea that a jury of close peers are going to decide the deletion test, and if you pass, that's flawed in my opinion, because the end culture, we don't have time for this, but the end culture of science is, you know, people aren't like helping each other ou…”
Huberman: Schizophrenia Lacks Strong Research Lobby Despite Affecting 1% of Population
“So where, the reason we don't have a cure for schizophrenia, even though it's one percent of the world's population, is, sadly, it tends to run in families. There's not a strong lobby for research on schizophrenia. The director of NIMH told me that, former dir…”
Indirect research cost cuts will disproportionately harm public universities
“A severe cut to the indirects, while on the face of it might sound good, that's going to disproportionately hurt the public schools without large endowments, ok, because they don't have money to dip into.”
Huberman: GLP-1 drugs ended the debate on the cause of obesity
“This peptide acts at the level of the brain and the gut to make people feel more full. It also, by the way, shut down the debate as to why people are fat. It's because they eat too much. Right? They eat more than they burn. Remember people used to argue about …”
Stem cell treatments are not yet ready for clinical use
“Is this to say that stem cells are bad? No, they're not ready for clinical use yet. And the United States has been very careful about things like this”
MDMA achieves 60% to 70% remission rates for PTSD
“The remission rates on PTSD, by the way, from properly dosed and spaced MDMA is remarkable up to somewhere between 60 and 70% remission rates on PTSD.”
Huberman: Joe Rogan's reach is 10x all major news hubs combined
“Rogan's reach is, like, beyond. I know the numbers. I, I'm not gonna talk about his numbers, but it's like, it's an order of magnitude greater than all the other major news hubs combined.”
Huberman: Sports regulators enforce upper limits on caffeine intake
“It's definitely a performance enhancer. So much so that, you know the people that regulate this stuff in sport set an upper limit on the milligrams of caffeine that you can ingest.”
Huberman says Pinealon peptide doubled his REM sleep to three hours
“I've tried it. I don't take it any longer. I tried it for a little while and it doubled my REM sleep. I was getting close to three hours of REM sleep per night. It's thought to increase regeneration or the health of pineal sites, the pineal, which make melaton…”
Huberman: Retatrutide caused one-third body weight loss in trials
“The interesting thing here is that in a phase three clinical trial in humans, it caused up to one third loss of body weight. So a loss of one third of body weight in about six months time. And it seems like there's some degree of muscle sparing.”
Huberman started microdosing testosterone cypionate at age 45 to maintain fertility
“You know, I've talked about the fact that at 45, I'm 50 now, 45 years old, I started taking a micro dose. Of Cipionate. Microdose. But micro, so I maintain fertility. I've checked that. I take HCG, et cetera.”
Huberman: Sunosi Is a Promising Non-Amphetamine ADHD Alternative
“It's designed, excuse me, designed for excessive daytime sleepiness called Sunosi, which it's kind of a dirtier hit of the dopamine and epinephrine and a little bit serotonin receptors that is promising for ADHD. That's a non-amphetamine ADHD drug. That's very…”
Huberman: NIH funds most US basic research and clinical trials
“Most of the basic research and clinical trials that are run in the United States are funded by the NIH.”
Huberman: Majority of Nobel Prizes in medicine originated from NIH funding
“The majority of Nobel Prizes has, in physiology and medicine, ah, and chemistry and related fields have come from work that was Either initially seeded by or certainly supported by the NIH.”
Huberman: Administration potentially restructuring NIH from 20+ institutes to eight
“The current administration seems to be taking a more like, they're gonna revise the way that NIH is structured potentially, 20 plus institutes down to eight, so all of it looks like downsizing.”
Huberman: BPC-157 has solid animal studies but zero human clinical trials
“Like BPC- one five seven, right? You hear about that all the time is, will it accelerate healing? You know, the animal studies are solid. There's no human studies.”
Huberman: Optimal Science Funding Gives Young Researchers Autonomy to Iterate Quickly
“You get money, you give it to young people, and you get the fuck out of their way and let them try. And then when they don't work, you guide them and you say, listen, like you're wasting your time, move on. And eventually you get hits. And then if you compile …”
Most Nobel Prizes in medicine stem from NIH-funded work
“The majority of Nobel prizes has in physiology and medicine and chemistry and related fields have come from work that was either initially seeded by, or certainly supported by the NIH.”
Huberman discloses partial ownership of Mateina alongside SciComm and Tiny
“I mean, we partnered with Matina, so I'm a partial owner with SciComm. You guys know Rob and the rest of the guys at SciComm, Andrew Wilkinson from Tiny. And we are available online through Matina, through Amazon. We launched in Whole Foods, in Costco, Canada,…”
Huberman locks his social media smartphone in a timed box daily
“I took my, an old phone. I put social media on that phone so that if people text me social media links, I can't open them. It also means that when I take out that phone, I'm posting or commenting or doing that. And I keep it in this lockbox, which is like a su…”
Huberman: Mental self-testing extends text retention up to a year
“In fact, there was a beautiful study done where they have people read some, a passage once, twice, three times, or four times versus reading it just once and then self-testing on it in their mind at some point later. And the self-testing in your mind, what do …”