People, every show

DJ Kleinbaum

On 1 show, 1 appearance. The Shows tab opens the full record on each.

1shows
1appearances
12statements
3resolved
2supported
0contradicted
67%fully supported

Everything DJ Kleinbaum said on any show that made the record, most notable first. Each card names its show and opens the statement there.

a16z Assertion Not checkable as stated
Laboratory virtualization helps solve the reproducibility crisis in scientific research
“The other important thing that is not necessarily obvious is this helps solve the reproducibility issue that we have in science.”
DJ Kleinbaum Jul 15, 2017 ▶ 9:04 DJ Kleinbaum
a16z Assertion Partly supported
Typical biotech Series A rounds reached $20M to $40M in 2017
“Nowadays a biotech company might raise 20, 30, forty million dollars for a first round of financing, and we raised a tiny fraction of that”
DJ Kleinbaum Jul 15, 2017 ▶ 2:18 DJ Kleinbaum
a16z Insight
Automation allows lean biotech startups to match big pharma research output
“You can do, ah, the same amount of work if you just make your scientists that many times more efficient than a company, than those who work at a big pharma company or at one of these other biotech firms.”
DJ Kleinbaum Jul 15, 2017 ▶ 2:43 DJ Kleinbaum
a16z Disclosure
Emerald Therapeutics taught every scientist on its staff how to code
“We decided to teach every scientist we hired, so organic chemists, molecular biologists, geneticists, you named it, how to write code.”
DJ Kleinbaum Jul 15, 2017 ▶ 4:50 DJ Kleinbaum
a16z Insight
Emerald Cloud Lab is virtualization like AWS, not outsourcing like CROs
“Be, it's not outsourcing, it's virtualization, so we are much more similar to Taiwan Semiconductor or Amazon Web Services than we are to any of these CROs”
DJ Kleinbaum Jul 15, 2017 ▶ 8:04 DJ Kleinbaum
a16z Insight
Untracked variables, not fraud, drive the scientific reproducibility crisis
“Maybe a tiny fraction of that might be malfeasance, but most scientists are trying really hard to, like, convey the results they have gotten and how they got them. The problem is, is that when you're doing that, when you're doing everything by hand, and you're…”
DJ Kleinbaum Jul 15, 2017 ▶ 9:38 DJ Kleinbaum
a16z Assertion Not checkable as stated
Emerald Cloud Lab captures all variables for push-button experiment reproducibility
“Every scientifically relevant variable is captured in lab automation and robotics. We have the fully detailed look at what your, what the world looked like when you ran that experiment. So therefore you can go back and get push button reproducibility because y…”
DJ Kleinbaum Jul 15, 2017 ▶ 10:17 DJ Kleinbaum
a16z Insight
Cloud lab turnaround must match Amazon Prime speed to be useful
“This needs to be like the Amazon Prime of life sciences research, because if there's too long between when you submit your experiment and when we do it, it's not going to be useful to you”
DJ Kleinbaum Jul 15, 2017 ▶ 15:11 DJ Kleinbaum
a16z Assertion Supported
Emerald Cloud Lab lets scientists globally run experiments remotely in SF
“So we have an application, so scientists anywhere in the world can design an experiment as if they are standing in front of the instrument themselves, That experiment then runs at our essential facility in South San Francisco.”
DJ Kleinbaum Jul 15, 2017 ▶ 0:23 DJ Kleinbaum
a16z Assertion Supported
Emerald Cloud Lab captures full environmental and maintenance metadata for experiments
“But it's not just the data that we send back for that particular experiment. It's all of the other meta and ancillary data around that. So things like For the instrument they ran it on, when was the last time we ran controls on that instrument to verify that i…”
DJ Kleinbaum Jul 15, 2017 ▶ 0:42 DJ Kleinbaum
a16z Assertion Not checkable as stated
Emerald Cloud Lab executes submitted experiment protocols within 48 hours
“So once you've done this a database succession number gets created, which is the number for this protocol. It gets sent to our queue, and then within 48 hours it will be running on one of our instruments.”
DJ Kleinbaum Jul 15, 2017 ▶ 14:56 DJ Kleinbaum
a16z Assertion Not checkable as stated
Typical life science experiments involve 80 to 100 controllable variables
“For any experiment, there may, might be 80 or a hundred different possible variables that you could change.”
DJ Kleinbaum Jul 15, 2017 ▶ 13:26 DJ Kleinbaum

One line per show, most statements first. The link opens DJ's full record on that show: the calibration, argument clarity, speaking style and every statement made there.

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a16zLEDGER 1 12 67% 2/3 full record on the a16z Podcast →
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