Nucleophilic Elbow

topic on 1 show · 1 statements across 1 episodes

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Sparse autoencoders found a single learned feature for nucleophilic elbows in ESMC
“You know, what we found basically is that the model has a kind of a single feature for this nucleophilic elbow and is activating across these like very evolutionarily diverse families, you know, really completely different structural topologies, proteins that …”
Alex Rives May 27, 2026 ▶ 12:59 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

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