Moderna

“And what we showed at ASCO and we published from a phase two study, but we believe it's the same thing in the phase three, because it's mechanistic, is that around 99 zero percent of the antigen are different patient to patient.”

“The factory is ready in Massachusetts, but we have figured out how to make and scale a product for every human being at the time.”

“Because the algorithm from the phase three was the same from the phase two, was the same from the phase one. But because we've been doing this for 10 years, it's a 10 year old algorithm.”

“It's the first time that there is an agent In melanoma that is better than Ketudra alone.”

“So indeed last week now we shared the news with our colleagues at Merck that after working 10 years on the individualized treatment against cancer using mRNA technology, that the phase three was positive.”

“As you mentioned, CAR-T, CAR-T was also approved in the same way as we believe Intesmiran will be, which is as a process BLA not a product BLA.”

“But now we don't make it with plasmid growing E. Coli or whatever. We make it all synthetic. So it's all enzymatic in liquid, in water.”

“Well, it's exactly the same for Intismaran, which is the current version of Intismaran that Moderna is the worst version of Intismaran you're going to see for the rest of medical history.”

“So the time is around 42 days now, needle to needle. So from taking the biopsy to getting the vaccine in the hospital ready for you.”

“We select the 34 that we believe are the most relevant, and we stitch them together into one big mRNA molecule, which we make in thirty-ish days for you, that is injected then in a hospital intramuscularly.”

“With all technology, I cannot speak about all the mRNA companies that have different mRNAs, different lipids, and so on, but with all technology, when we inject our mRNA in a muscle, whether it's a COVID shot, a flu shot, or this cancer treatment, basically th…”

“Here it's the first time there is a cancer vaccine working. The field, as you know, has been doing that for 20 plus years. I think more than a thousand clinical trials that have all failed.”

“We announced in the spring of 2026, starting a phase three study for patients with stage one lung cancer, but as Intismarine, so Moderna's product, as a monotherapy without checkpoint.”

“The facility will be able to make the one in Marlboro, Mass, tens of thousands of doses.”

“What we announced last week is that we met the primary End point of a study, which was recurrence-free survival, i.e. People having the cancer back or dying, that we met, and then to our own surprise, because this was the first interim analysis. This is not th…”

“We showed it even at ASCO this year, where we took the blood before treatment, after treatment of cancer patients, melanoma, with all technology, and we showed that I don't think we have an expansion of the T-cells, But we have de novo, so new T cells being cr…”

“As we said about the phase two data, 80% of people are disease-free after five years.”