Bancel: Moderna Phase 3 trial met primary and secondary endpoints at first interim analysis
Stéphane Bancel · Inside Moderna’s Biggest mRNA Test Since COVID · Sep 2, 2026 · at 3:42
Moderna CEO Stéphane Bancel details the specific clinical endpoints achieved in their Phase 3 melanoma mRNA vaccine study with Jorge Conde on The a16z Show.
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“What we announced last week is that we met the primary End point of a study, which was recurrence-free survival, i.e. People having the cancer back or dying, that we met, and then to our own surprise, because this was the first interim analysis. This is not the end of a study. It's the first interim analysis of a study, and what was a surprise event to us is we met the secondary endpoint, which was distant metastasis-free survival, which is, of course, takes more time to mature Because it means that you have distance metastases from your primary tumor. And we also made that endpoint, which was great.”
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