Michel Del Buono, CIO of Andreessen Horowitz's multi-family office Perennial, discusses the most common wealth management mistakes made by newly liquid startup founders.
“I'll see someone with their very first liquidity, the very, very first liquidity, they take it and instead of doing something a little bit safe in case there's a rainy day, they turn around and they go put it in a bunch of like very early stage startups.
Often referred to by their friends, right?
And you just sort of sit there and you're like, listen, if you're going to do venture, at least try to do in a systematic way, not take, you know, 80% of what you just got and hand it to your three friends.
And almost, almost always this ends in tears.
Maybe I'm being exaggerating, but very rarely do those outcomes happen the same.”
quote is from the automated transcript, cleaned for reading:
filler sounds and stutters are removed, nothing is rephrased. names can be misheard
(the analysis reads context, assessments check outside sources). how →
More from Michel Del Buono
AssertionNot checkable as stated
Del Buono: Most tech-focused RIAs have at most one or two professional investors
“So a lot of these firms do not have professional investors. So I often ask people as a quiz how many professional investors do you think are in, you know, RIA XYZ? And people will answer, I mean, percent, right? People answer me, 20%, 50%, 30%, but the number …”
Michel Del BuonoMar 27, 2026▶ 21:52Inside Marc Andreessen & Ben Horowitz’s Multi-Family Office · Sourcery with Molly O'Shea
Opinion
Del Buono: Most Secondary Volume Flows Through Questionable SPVs
“The vast majority of the volume goes through these sort of questionable SPDs”
Michel Del BuonoMar 27, 2026▶ 44:25Inside Marc Andreessen & Ben Horowitz’s Multi-Family Office · Sourcery with Molly O'Shea
Opinion
Del Buono: AI Startup Check Sizes Make Fund Scale Essential in Venture
“All asset management industries have some scale benefits to them. Venture traditionally had less and now has a lot. So if you're going to back a new AI startup, you can't show up with a million dollar check or two million dollar check that it's useless or let …”
Michel Del BuonoMar 27, 2026▶ 49:06Inside Marc Andreessen & Ben Horowitz’s Multi-Family Office · Sourcery with Molly O'Shea
Insight
Attorneys and CPAs ignore tax-loss strategies that rival complex trust structures
“Where I find that people have difficulty is you hire attorneys, right, and they're going to tell you everything about, or CPAs, about these trusts, but they're not going to have the knowledge
To compare that and contrast that to an investment strategy that gen…”
Michel Del BuonoMay 22, 2026▶ 4:25CIO of Marc & Ben's Multi-Family Office: SpaceX IPO, Anthropic & OpenAI · Sourcery with Molly O'Shea
Insight
Wealth managers push diversification strictly to earn fees on founder stock
“Wealth managers, asset managers, It's very self-serving for them to say, hey, you should liquidate everything because obviously they can't, they're not going to charge you fees on your concentrate position. It's your stock. You brought it to the table, but the…”
Michel Del BuonoMay 22, 2026▶ 12:57CIO of Marc & Ben's Multi-Family Office: SpaceX IPO, Anthropic & OpenAI · Sourcery with Molly O'Shea
Insight
Winning concentrated startup stock usually continues to perform well post-liquidity
“History has shown that hanging onto your stock Generally speaking, not always. There are counter examples, of course, to everything. Generally, you know, that stock that got you to the liquidity point will probably continue to do pretty well.”
Michel Del BuonoMay 22, 2026▶ 13:43CIO of Marc & Ben's Multi-Family Office: SpaceX IPO, Anthropic & OpenAI · Sourcery with Molly O'Shea
Made with StarZero
Turn any episode into a week of clips.
This entire site, over 160 episodes transcribed, diarized, checked and made playable,
runs on the StarZero media pipeline. Drop in your own episode and the podcast clipper finds the
moments worth sharing, cuts them, captions them, and reframes them for every feed.
We use essential cookies to make the site work. With your permission we
also use analytics cookies (Google Analytics and Mixpanel) to understand
usage and improve StarZero. See our Cookie Policy.