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Johnny Yu

Co-Founder & CSO, Tahoe Therapeutics · 1 appearance on the record.

computed by AI from the episodes · how this works → · full disclaimer →

founderscientistexecutive@IAmJohnnyYu ↗LinkedIn ↗tahoebio.ai ↗

Johnny Yu co-founded Tahoe Therapeutics to generate in vivo single-cell perturbation datasets for training AI models of human cellular responses. Holding a Ph.D. from UCSF, he developed the company's Mosaic platform and spearheaded the Tahoe-100M atlas in partnership with the Arc Institute.

5statements → 4claims → 2claims resolved → 3.6/5average certainty → 2/5average debate potential →

1 supported 1 partly supported 0 contradicted 2 not checkable as stated how the 4 claims stand · each chip opens the sources

1 prediction · 3 assertions · 1 disclosure · every statement was checked. The prediction and assertions are the 4 claims: statements the public record can support or contradict. 2 are resolved, and 2 name no date, number or outcome precise enough to check. Everything else (opinions, insights, what ifs, disclosures) can never be settled by the record, so it carries no assessment.

The record, in short

What the tape says about how Johnny argues and how the claims held up. Everything they said, and everything said about them, is in the tabs below.

Their most notable supported claim

Assertion Supported
Johnny Yu: Tahoe-100 is the world's largest single-cell RNA sequencing dataset
“So Tahoe 100 is the world's biggest single cell RNA sequencing data set, and it enables basically a ton of machine learning applications, including things like the virtual cell, but it also enables a lot of drug discovery applications, and broadly in the conte…”
Johnny Yu Feb 25, 2025 ▶ 1:40 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

How they sound: not measured why? →

We measure speaking style by listening to the audio itself, and a fair number needs at least 2,000 words from one person on tape we have measured. There is too little of Johnny Yu on measured tape to publish a rate. This says nothing about how they speak.

Everything Johnny Yu said on No Priors that made the record, most notable first. Filter by type, assessment or year in the ledger →

Prediction Not checkable as stated
Yu: Virtual cell models will directly design disease-reversing drugs
“A big part of our future vision and roadmap is that we think there will be a moment where from a virtual cell model, a drug is spit out, and basically the drug will actually cause a healthy disease cell to become a healthy cell again.”
Johnny Yu Feb 25, 2025 ▶ 37:03 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
Assertion Partly supported
Yu: Tahoe dataset doubles a decade of cumulative single-cell data
“And so this data set, it is basically doubling the size of all the data that's out there cumulatively over the past decade. It covers 50 different cancer models from different patients, so it's cells from 50 different patients. 1200 drug treatments, so it's a …”
Johnny Yu Feb 25, 2025 ▶ 9:51 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
Assertion Not checkable as stated
Yu: Cancer perturbation pathways apply broadly to neuroscience and immunology
“This data set, even though it's heavily based around these kinds of chemical perturbations of cancer, they also, these pathways are so conserved and fundamental that they broadly apply to the neuroscience space or like to just immune cell development in genera…”
Johnny Yu Feb 25, 2025 ▶ 15:53 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
Assertion Supported
Johnny Yu: Tahoe-100 is the world's largest single-cell RNA sequencing dataset
“So Tahoe 100 is the world's biggest single cell RNA sequencing data set, and it enables basically a ton of machine learning applications, including things like the virtual cell, but it also enables a lot of drug discovery applications, and broadly in the conte…”
Johnny Yu Feb 25, 2025 ▶ 1:40 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute
Disclosure
Yu: Vevo generated Tahoe dataset with four people in three days
“Well, it ended up being actually four people from Vivo, and we did it, I think, over like three days in the end.”
Johnny Yu Feb 25, 2025 ▶ 31:20 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

Appearances (1)

EpisodeDateSpeaking time
No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute Feb 25, 2025 4m
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