Assertion Supported
Guo: No open-source model matches GPT-3.5, GPT-4, or Claude quality
“So there's nothing out there today in open source that is like GPT four, three, five or anthropic cloud quality, right? So there is a, there's one player out in front and that's open AI”
Insight
Guo: Retraining the same size model is 5x cheaper on the second run
“It's going to be five X cheaper to train the same size model the second time around, like, once you've made your mistakes and know what you're doing.”
Prediction Held up
Guo: An open-source model matching GPT-3.5 will arrive within a year
“Like if I were a betting woman and I am, I bet there's a three, five level model in the open source ecosystem within a year.”
Insight
Guo: Autonomous agents orchestrate LLM loops without changing model architecture
“The basic idea is to orchestrate LMs in this like iterative loop towards some high level goal. Where they're doing planning, and if memory, and prioritization, reflection, and so you're not necessarily changing the architecture of the LLM itself, but this orch…”
Prediction Not checkable as stated
Gil: 2024 election will be the pivotal moment driving AI regulation
“The big pivot point for regulation may actually come during the 20, 24 election. Because I think that's the moment that people will show examples of AI being used to influence the election or influence voting behavior, just like ads influence voting behavior, …”
Insight
Guo: AI alignment research cannot be separated from capability research
“Alignment research is very tied to capability research, right? And so it's sort of impossible to be like, we're going to stop making any progress on research. But figure out how to control this stuff.”
Prediction Not checkable as stated
Gil: AI poses no existential threat to humanity within ten years
“So you need physical form for the AI in order for it to truly be an existential threat. And that's why if I were to focus on an area, it'd probably be robotics or something like that, because that's where you suddenly give physical form to something. And if yo…”
Assertion Supported
Guo: Midjourney has a completely investor-free cap table
“Like any investor that claims they knew image generation
From text was a killer use case, like, a year or two ago, besides you, is just empirically wrong, given David's completely investor-free cap table and amazing business, right, so.”
Opinion
Gil: Elon Musk's AI moratorium call was self-serving given his LLM startup
“Musk was asking for a six month moratorium on progress, which seems to me very self-serving if you're simultaneously starting an LLM company, you know.”
Prediction Not checkable as stated
Gil: AI value capture will likely be 80% incumbents, 20% startups
“And it feels like in this wave, it's probably eighty-twenty again, right? It's probably, Google will probably become a player, right? OpenAI is closely aligned with Microsoft. And then, you know Salesforce with AI is probably Salesforce, right? It probably isn…”
Prediction Not checkable as stated
Gil: AI will be adopted fastest in healthcare operations and delivery
“Usually I think the places in healthcare where this will really get applied fast. Is on the more operational or services intensive related side. It's healthcare delivery. It's lowering the cost of a doctor visit or telemedicine. It's making payments easier and…”
Assertion Contradicted
Gil: No major drug-developing biotech founded since late 1980s hit $30B-$50B
“The last time a biotech company hit, I don't know what it is, 3040, fifty billion dollars in market cap, something like that. The last year such a thing was founded was in the late eighties. So it's been at this point, what is that? 35, 40 years without a new …”
Assertion Supported
Gil: Top four or five tech companies equal the entire biopharma market cap
“If you add up the top four or five tech companies, their market cap equals the entire industry for biopharma.”