May 3, 2023 · 45m · no-priors

No Priors Ep. 3 | With Stability AI’s Emad Mostaque

Emad Mostaque · 31m spoken Elad Gil · 5m spoken Sarah Guo · 3m spoken
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In this episode of No Priors, Stability AI founder Emad Mostaque discusses the transformative power of open-source artificial intelligence, arguing for modular architectures, public infrastructure, and decentralized models over centralized Big Tech monopolies.

How this conversation actually went

Every chapter scored 0–10 on four independent dynamics. Hover any point for the reasoning behind the score. The hosts hold 19.9% of the talking time here. How this is scored →

The hosts as informed peer 4.3 Guest teaching 2.8 Guest disagreement 1.0 The hosts pushing back 0.9
05100:0015:0030:0045:000:05–2:14 · The hosts as informed peer 2/10 Emad Mostaque's Journey from Finance to AI Sarah Guo opens with a standard biographical question regarding Emad Mostaque's transition from hedge funds to AI. Mostaque delivers an uninterrupted introductory monologue detailing his son's diagnosis and his philanthropic initiatives.2:15–5:58 · The hosts as informed peer 3/10 Origins of Stability AI and Open Source Communities Guo sets context around scaling laws and open community efforts like EleutherAI. Mostaque explains his personal funding of early generative notebooks, his aphantasia, and the transition from a DAO concept to commercial open source.5:59–11:36 · The hosts as informed peer 4/10 Open Source Infrastructure and Supercomputing Compute Elad Gil probes how open-source foundation models will survive capital requirements versus closed ecosystems. Mostaque makes the bold claim that Stability has access to more compute than Google or Microsoft via national exascale supercomputers and outlines a multi-stage training paradigm.11:37–15:53 · The hosts as informed peer 5/10 Multimodal Initiatives and Computational Biology at Stability Gil asks for a breakdown of Stability's multimodal and computational biology initiatives. Mostaque details edge distillation, OpenFold, and BioLM while emphasizing focus on private regulated data.15:54–22:47 · The hosts as informed peer 7/10 Global AI Deployment and Leapfrogging Western Systems Gil offers strong domain context by citing the 1970s Stanford MYCIN expert system to question healthcare AI adoption friction. Guo supplements with an analogy on historical mobile tech leapfrogging in East Asia, which Mostaque validates using developing world deployment figures.22:47–27:43 · The hosts as informed peer 4/10 The Future of Media Creation and Augmentation Versus AGI Guo cites Sam Altman's view that image generation is not core to AGI. Mostaque directly dismisses OpenAI's monolithic AGI framing, arguing instead for human intelligence augmentation and modular federated models.27:44–32:35 · The hosts as informed peer 5/10 Language Model Strategies and Commercial Architecture Guo highlights specific training run parameters (150,000 A100 hours) to probe language model strategies. Mostaque details small-to-medium specialized models, RWKV attention-free architectures, and custom enterprise deployments.32:36–36:44 · The hosts as informed peer 5/10 Digital Democracy, Governance, and Model Limitations Gil references sci-fi literature (Lady of Mazes) regarding algorithmic governance representation. Mostaque discusses multi-agent consensus and explains why LLMs must be treated as creative lossy compression rather than factual databases.36:44–44:24 · The hosts as informed peer 4/10 AI Safety, Regulation, and Content Attribution Gil and Guo explore alignment, commercial ad manipulation, and data attribution regulation. Mostaque advocates for compute registration above specific FLOP thresholds and provenance metadata standards like Content Authenticity.0:05–2:14 · Guest teaching 1/10 Emad Mostaque's Journey from Finance to AI Sarah Guo opens with a standard biographical question regarding Emad Mostaque's transition from hedge funds to AI. Mostaque delivers an uninterrupted introductory monologue detailing his son's diagnosis and his philanthropic initiatives.2:15–5:58 · Guest teaching 2/10 Origins of Stability AI and Open Source Communities Guo sets context around scaling laws and open community efforts like EleutherAI. Mostaque explains his personal funding of early generative notebooks, his aphantasia, and the transition from a DAO concept to commercial open source.5:59–11:36 · Guest teaching 4/10 Open Source Infrastructure and Supercomputing Compute Elad Gil probes how open-source foundation models will survive capital requirements versus closed ecosystems. Mostaque makes the bold claim that Stability has access to more compute than Google or Microsoft via national exascale supercomputers and outlines a multi-stage training paradigm.11:37–15:53 · Guest teaching 3/10 Multimodal Initiatives and Computational Biology at Stability Gil asks for a breakdown of Stability's multimodal and computational biology initiatives. Mostaque details edge distillation, OpenFold, and BioLM while emphasizing focus on private regulated data.15:54–22:47 · Guest teaching 3/10 Global AI Deployment and Leapfrogging Western Systems Gil offers strong domain context by citing the 1970s Stanford MYCIN expert system to question healthcare AI adoption friction. Guo supplements with an analogy on historical mobile tech leapfrogging in East Asia, which Mostaque validates using developing world deployment figures.22:47–27:43 · Guest teaching 4/10 The Future of Media Creation and Augmentation Versus AGI Guo cites Sam Altman's view that image generation is not core to AGI. Mostaque directly dismisses OpenAI's monolithic AGI framing, arguing instead for human intelligence augmentation and modular federated models.27:44–32:35 · Guest teaching 3/10 Language Model Strategies and Commercial Architecture Guo highlights specific training run parameters (150,000 A100 hours) to probe language model strategies. Mostaque details small-to-medium specialized models, RWKV attention-free architectures, and custom enterprise deployments.32:36–36:44 · Guest teaching 3/10 Digital Democracy, Governance, and Model Limitations Gil references sci-fi literature (Lady of Mazes) regarding algorithmic governance representation. Mostaque discusses multi-agent consensus and explains why LLMs must be treated as creative lossy compression rather than factual databases.36:44–44:24 · Guest teaching 2/10 AI Safety, Regulation, and Content Attribution Gil and Guo explore alignment, commercial ad manipulation, and data attribution regulation. Mostaque advocates for compute registration above specific FLOP thresholds and provenance metadata standards like Content Authenticity.0:05–2:14 · Guest disagreement 0/10 Emad Mostaque's Journey from Finance to AI Sarah Guo opens with a standard biographical question regarding Emad Mostaque's transition from hedge funds to AI. Mostaque delivers an uninterrupted introductory monologue detailing his son's diagnosis and his philanthropic initiatives.2:15–5:58 · Guest disagreement 0/10 Origins of Stability AI and Open Source Communities Guo sets context around scaling laws and open community efforts like EleutherAI. Mostaque explains his personal funding of early generative notebooks, his aphantasia, and the transition from a DAO concept to commercial open source.5:59–11:36 · Guest disagreement 2/10 Open Source Infrastructure and Supercomputing Compute Elad Gil probes how open-source foundation models will survive capital requirements versus closed ecosystems. Mostaque makes the bold claim that Stability has access to more compute than Google or Microsoft via national exascale supercomputers and outlines a multi-stage training paradigm.11:37–15:53 · Guest disagreement 0/10 Multimodal Initiatives and Computational Biology at Stability Gil asks for a breakdown of Stability's multimodal and computational biology initiatives. Mostaque details edge distillation, OpenFold, and BioLM while emphasizing focus on private regulated data.15:54–22:47 · Guest disagreement 1/10 Global AI Deployment and Leapfrogging Western Systems Gil offers strong domain context by citing the 1970s Stanford MYCIN expert system to question healthcare AI adoption friction. Guo supplements with an analogy on historical mobile tech leapfrogging in East Asia, which Mostaque validates using developing world deployment figures.22:47–27:43 · Guest disagreement 3/10 The Future of Media Creation and Augmentation Versus AGI Guo cites Sam Altman's view that image generation is not core to AGI. Mostaque directly dismisses OpenAI's monolithic AGI framing, arguing instead for human intelligence augmentation and modular federated models.27:44–32:35 · Guest disagreement 1/10 Language Model Strategies and Commercial Architecture Guo highlights specific training run parameters (150,000 A100 hours) to probe language model strategies. Mostaque details small-to-medium specialized models, RWKV attention-free architectures, and custom enterprise deployments.32:36–36:44 · Guest disagreement 1/10 Digital Democracy, Governance, and Model Limitations Gil references sci-fi literature (Lady of Mazes) regarding algorithmic governance representation. Mostaque discusses multi-agent consensus and explains why LLMs must be treated as creative lossy compression rather than factual databases.36:44–44:24 · Guest disagreement 1/10 AI Safety, Regulation, and Content Attribution Gil and Guo explore alignment, commercial ad manipulation, and data attribution regulation. Mostaque advocates for compute registration above specific FLOP thresholds and provenance metadata standards like Content Authenticity.0:05–2:14 · The hosts pushing back 0/10 Emad Mostaque's Journey from Finance to AI Sarah Guo opens with a standard biographical question regarding Emad Mostaque's transition from hedge funds to AI. Mostaque delivers an uninterrupted introductory monologue detailing his son's diagnosis and his philanthropic initiatives.2:15–5:58 · The hosts pushing back 0/10 Origins of Stability AI and Open Source Communities Guo sets context around scaling laws and open community efforts like EleutherAI. Mostaque explains his personal funding of early generative notebooks, his aphantasia, and the transition from a DAO concept to commercial open source.5:59–11:36 · The hosts pushing back 1/10 Open Source Infrastructure and Supercomputing Compute Elad Gil probes how open-source foundation models will survive capital requirements versus closed ecosystems. Mostaque makes the bold claim that Stability has access to more compute than Google or Microsoft via national exascale supercomputers and outlines a multi-stage training paradigm.11:37–15:53 · The hosts pushing back 0/10 Multimodal Initiatives and Computational Biology at Stability Gil asks for a breakdown of Stability's multimodal and computational biology initiatives. Mostaque details edge distillation, OpenFold, and BioLM while emphasizing focus on private regulated data.15:54–22:47 · The hosts pushing back 4/10 Global AI Deployment and Leapfrogging Western Systems Gil offers strong domain context by citing the 1970s Stanford MYCIN expert system to question healthcare AI adoption friction. Guo supplements with an analogy on historical mobile tech leapfrogging in East Asia, which Mostaque validates using developing world deployment figures.22:47–27:43 · The hosts pushing back 1/10 The Future of Media Creation and Augmentation Versus AGI Guo cites Sam Altman's view that image generation is not core to AGI. Mostaque directly dismisses OpenAI's monolithic AGI framing, arguing instead for human intelligence augmentation and modular federated models.27:44–32:35 · The hosts pushing back 0/10 Language Model Strategies and Commercial Architecture Guo highlights specific training run parameters (150,000 A100 hours) to probe language model strategies. Mostaque details small-to-medium specialized models, RWKV attention-free architectures, and custom enterprise deployments.32:36–36:44 · The hosts pushing back 0/10 Digital Democracy, Governance, and Model Limitations Gil references sci-fi literature (Lady of Mazes) regarding algorithmic governance representation. Mostaque discusses multi-agent consensus and explains why LLMs must be treated as creative lossy compression rather than factual databases.36:44–44:24 · The hosts pushing back 2/10 AI Safety, Regulation, and Content Attribution Gil and Guo explore alignment, commercial ad manipulation, and data attribution regulation. Mostaque advocates for compute registration above specific FLOP thresholds and provenance metadata standards like Content Authenticity.

speaking balance: gold is the hosts, purple is the guest (3 minute bins)

0:00 · the hosts 32.2% · guest 67.8%0:00 · the hosts 32.2% · guest 67.8%3:00 · the hosts 2.1% · guest 97.9%3:00 · the hosts 2.1% · guest 97.9%6:00 · the hosts 16.3% · guest 83.7%6:00 · the hosts 16.3% · guest 83.7%9:00 · the hosts 24.5% · guest 75.5%9:00 · the hosts 24.5% · guest 75.5%12:00 · the hosts 6.3% · guest 93.7%12:00 · the hosts 6.3% · guest 93.7%15:00 · the hosts 43.4% · guest 56.6%15:00 · the hosts 43.4% · guest 56.6%18:00 · the hosts 34.4% · guest 65.6%18:00 · the hosts 34.4% · guest 65.6%21:00 · the hosts 19.4% · guest 80.6%21:00 · the hosts 19.4% · guest 80.6%24:00 · the hosts 10.6% · guest 89.4%24:00 · the hosts 10.6% · guest 89.4%27:00 · the hosts 14.9% · guest 85.1%27:00 · the hosts 14.9% · guest 85.1%30:00 · the hosts 17.6% · guest 82.4%30:00 · the hosts 17.6% · guest 82.4%33:00 · the hosts 15.6% · guest 84.4%33:00 · the hosts 15.6% · guest 84.4%36:00 · the hosts 37.8% · guest 62.2%36:00 · the hosts 37.8% · guest 62.2%39:00 · the hosts 5.8% · guest 94.2%39:00 · the hosts 5.8% · guest 94.2%42:00 · the hosts 18.2% · guest 81.8%42:00 · the hosts 18.2% · guest 81.8%45:00 · the hosts 0% · guest 0%45:00 · the hosts 0% · guest 0%
Sharpest disagreement ▶ 26:02 Dismissal of OpenAI's AGI focus

Mostaque flatly dismisses Sam Altman's stance on image generation and AGI, asserting that monolithic elder-god AGI architectures are the wrong target compared to intelligence augmentation.

Hardest push from the hosts ▶ 17:31 Historical pushback on medical AI adoption barriers

Gil directly challenges the timeline for healthcare AI by pointing out that Stanford's MYCIN outperformed human physicians in the 1970s yet remained unadopted decades later.

Biggest teaching moment ▶ 35:50 Debunking LLMs as factual databases

Mostaque educates listeners on information theory, explaining that compressing terabytes of data into a few gigabytes inherently loses factual precision and turns models into fiction engines.

The host holds their own ▶ 17:31 Host demonstrates deep history of medical expert systems

Gil demonstrates deep technical history by citing the specific 1970s MYCIN infectious disease project to ground a speculative medical AI discussion in historical reality.

the scores for every segment, with the reasoning behind each
ChapterTopicThe hosts as informed peerGuest teachingGuest disagreementThe hosts pushing backWhy
Emad Mostaque's Journey from Finance to AI 2100 Sarah Guo opens with a standard biographical question regarding Emad Mostaque's transition from hedge funds to AI. Mostaque delivers an uninterrupted introductory monologue detailing his son's diagnosis and his philanthropic initiatives.
Origins of Stability AI and Open Source Communities 3200 Guo sets context around scaling laws and open community efforts like EleutherAI. Mostaque explains his personal funding of early generative notebooks, his aphantasia, and the transition from a DAO concept to commercial open source.
Open Source Infrastructure and Supercomputing Compute 4421 Elad Gil probes how open-source foundation models will survive capital requirements versus closed ecosystems. Mostaque makes the bold claim that Stability has access to more compute than Google or Microsoft via national exascale supercomputers and outlines a multi-stage training paradigm.
Multimodal Initiatives and Computational Biology at Stability 5300 Gil asks for a breakdown of Stability's multimodal and computational biology initiatives. Mostaque details edge distillation, OpenFold, and BioLM while emphasizing focus on private regulated data.
Global AI Deployment and Leapfrogging Western Systems 7314 Gil offers strong domain context by citing the 1970s Stanford MYCIN expert system to question healthcare AI adoption friction. Guo supplements with an analogy on historical mobile tech leapfrogging in East Asia, which Mostaque validates using developing world deployment figures.
The Future of Media Creation and Augmentation Versus AGI 4431 Guo cites Sam Altman's view that image generation is not core to AGI. Mostaque directly dismisses OpenAI's monolithic AGI framing, arguing instead for human intelligence augmentation and modular federated models.
Language Model Strategies and Commercial Architecture 5310 Guo highlights specific training run parameters (150,000 A100 hours) to probe language model strategies. Mostaque details small-to-medium specialized models, RWKV attention-free architectures, and custom enterprise deployments.
Digital Democracy, Governance, and Model Limitations 5310 Gil references sci-fi literature (Lady of Mazes) regarding algorithmic governance representation. Mostaque discusses multi-agent consensus and explains why LLMs must be treated as creative lossy compression rather than factual databases.
AI Safety, Regulation, and Content Attribution 4212 Gil and Guo explore alignment, commercial ad manipulation, and data attribution regulation. Mostaque advocates for compute registration above specific FLOP thresholds and provenance metadata standards like Content Authenticity.

Statements from this episode (24)

Opinion
Democratizing AI Is a Moral Imperative as Models Reach Superhuman Level
“More on that, a bit of a moral imperative to make this technology available to everyone because we're now going to very narrow superhuman performance and everyone should have access to that.”
Emad Mostaque May 3, 2023 ▶ 1:59
Disclosure
Emad Mostaque Personally Funded Early Open-Source AI and Midjourney Grants
“So I started supporting the whole space at Luther and beyond, giving jobs to the developers, compute for the model creators, funding the various notebooks from disco diffusion to these other things, you know, giving grants to people like mid journey that were …”
Emad Mostaque May 3, 2023 ▶ 4:15
Disclosure
Stability AI Was Originally Conceived as a Decentralized Autonomous Organization
“And originally I thought you got communities, you gotta make them kind of coordinated. Could a DAO work or a DAO of DAOs? And that's how stability started. After about a week, I realized that was not gonna work and it was incredibly difficult. So then I figure…”
Emad Mostaque May 3, 2023 ▶ 4:44
Assertion Contradicted
Stability AI Repositories Beat Ethereum and Bitcoin Combined in GitHub Stars
“You know, on GitHub stars, we've overtaken Ethereum and Bitcoin cumulatively. It took them 10 years. We got there in like three, four months.”
Emad Mostaque May 3, 2023 ▶ 7:10
Assertion Not checkable as stated
Stability AI Has More Compute Available Than Microsoft or Google
“The reality is we have more compute available to us than Microsoft or Google.”
Emad Mostaque May 3, 2023 ▶ 9:33
Disclosure
Stability AI Secured a Seven Million Hour Grant on Summit Supercomputer
“So to give you an example, we just got a seven million hour grant on Summit, one of the fastest supercomputers in the US.”
Emad Mostaque May 3, 2023 ▶ 9:43
Prediction Open · timeframe May 2028
All Base Foundation Models Will Ultimately Open Source Their Pre-Training Phase
“So my take is that foundation models will all be open source for the deep learning phase.”
Emad Mostaque May 3, 2023 ▶ 10:19
Assertion Supported
Distilled Stable Diffusion Models Can Run Locally on iPhones in Seconds
“Now, as of the release of Distilled Stable Diffusion, it will run in a couple of seconds on an iPhone, and we have neural engine access, because our view of the future is creating models that aren't necessarily bigger, but that are customizable and editable.”
Emad Mostaque May 3, 2023 ▶ 12:37
Prediction Not checkable as stated
Computational Biology Will See Artificial Intelligence's Biggest Scientific Breakthroughs
“And then I think on a breakthrough side, computational biology will be the biggest one.”
Emad Mostaque May 3, 2023 ▶ 14:36
Disclosure
Stability AI Plans to Release an Open Medical Foundation Model
“We will release an open MedPalm model. Well, med stable GPT.”
Emad Mostaque May 3, 2023 ▶ 14:53
Disclosure
Stability AI Is Deploying Four Million Tablets to Children Across Malawi
“So right now we're deploying four million tablets to every child in Malawi.”
Emad Mostaque May 3, 2023 ▶ 18:42
Prediction Not checkable as stated
Emerging Market AI Systems Will Outperform the West Within Five Years
“I am certain that system will outperform anything in the West within five years.”
Emad Mostaque May 3, 2023 ▶ 19:11
Assertion Not checkable as stated
Movie Studios Are Already Saving Millions by Implementing Stable Diffusion Locally
“We are working with multiple movie studios at the moment who are saving millions of dollars, just implementing stable diffusion by itself, let alone these other technologies.”
Emad Mostaque May 3, 2023 ▶ 25:23
Opinion
OpenAI Is Incorrect That Image Generation Is Not Core to AGI
“I do believe that they are incorrect around multimodality being, or images being a core component of that.”
Emad Mostaque May 3, 2023 ▶ 26:26
Prediction Held up
Generative Image Models Will Soon Achieve 25 Frames Per Second
“With the additional breakthroughs that are coming through, it'll be 25 frame images a second. That's a hundred times speed up over a hundred times just from getting it out there and people interested in doing that.”
Emad Mostaque May 3, 2023 ▶ 30:08
Disclosure
Stability AI Is Exclusively Training Video Models on the Eros Bollywood Catalog
“So like now we're training on hundreds and soon thousands of Bollywood movies to create Bollywood video models with our partnership with Eros you know, and that is exclusively licensed.”
Emad Mostaque May 3, 2023 ▶ 31:25
Opinion
Only About 100 People Worldwide Possess Skills to Train Foundation Models
“There's only like a hundred people who can train models in the world. Like it's not really a science. It's more an art, like losses explode all over the place when you try to do something.”
Emad Mostaque May 3, 2023 ▶ 31:58
Opinion
Multi-Model Interactions Will Dominate the Future of AI Over Zero-Shot Models
“And again, I think this is the future, not just zero shot, multiple models interacting with each other is the way full stop.”
Emad Mostaque May 3, 2023 ▶ 35:08
Insight
Large Language Models Are Creative Fiction Engines Rather Than Factual Databases
“I do say these large models as well should be viewed as fiction, creative models, not fact models, because otherwise we've created the most efficient compression in the world. Does it make sense you can take terabytes of data and compress it down to a few giga…”
Emad Mostaque May 3, 2023 ▶ 36:14
Opinion
Large AI Model Runs Should Be Registered Like Dual-Use Biological Weapons
“I think that a productive outcome of that regulation is anything above a certain level of flops needs to be registered similar to, well, bio weapons and things that have the potential for dual use.”
Emad Mostaque May 3, 2023 ▶ 38:59
Prediction Not checkable as stated
Governments Will Eventually Pour Hundreds of Billions Into AGI Model Scaling
“When governments decide, and I don't believe they've decided yet, that having an AGI is the number one thing, tens of billions, hundreds of billions will go into building bigger models.”
Emad Mostaque May 3, 2023 ▶ 39:38
Assertion Not checkable as stated
Malicious Actors Already Possess Advanced AI Models and Thousands of A100 GPUs
“I think the bad guys, I'm going to put that in quotes have access to these models already and thousands and thousands of A-one hundreds.”
Emad Mostaque May 3, 2023 ▶ 42:51
Prediction Not checkable as stated
Small Hive Architecture AI Models Will Massively Outperform Large Monolithic Models
“I think that small models will outperform large models massively, like I said, the Hive model aspect”
Emad Mostaque May 3, 2023 ▶ 44:38
Prediction Held up
ChatGPT-Level AI Models Will Run Locally on Smartphones by 2028
“You will see ChatGPT level models running on the edge on smartphones in five years, which will be crazy.”
Emad Mostaque May 3, 2023 ▶ 44:38
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