The Ledger
Every statement that passed quotation and attribution checks. Mix any filter with any other: certainty 1/5, debate potential 5/5, or both at once.
why aren't all 8 resolved? a statement only gets an assessment when the public record can support or contradict it. opinions and what-ifs never can, and 2 checkable ones are still open, waiting for their date. predictions held up or didn't; assertions are supported or contradicted. on every card: ▮▮▮▮▮ certainty · ▮▮▮▮▮ debate potential. speakers are clickable
Chan: AI models will evaluate genetic variants of unknown significance
“And what you really want to do, and I think these models will be able to do is look at those variants and actually model out what is the impact in the different cells, how it influences cellular behavior and whether or not that is Tied to a pathway to disease …”
Chan: Philanthropies lack the clear performance dashboards companies use
“And the thing that in running a philanthropy, I'm incredibly envious of people who run companies is that like you guys can have a dashboard and there's like financial results and people tell you if you're on the right track on the wrong track and there's clari…”
Chan: Connecting AI researchers to wet-lab data collectors improves AI models
“Data is not just data. You guys know this, like you need to know sort of how the data was collected and from where and being able to connect the AI researchers to the folks who are actually gathering the data on a daily basis makes their work better.”
Chan: CZI Billion Cell Project takes months at fraction of historical cost
“Now we're doing the billion cell project and that is taking months and at a fraction of the price.”
Chan: Science has examined only a fraction of billions of human cell types
“We know there are billions of cell types in a human, and we've only truly looked at a fraction of them, and we looked at it in largely healthy cells.”
Chan: Predictive AI will de-risk bold, high-risk biological hypotheses
“Right now, because the wet lab is so expensive and relatively slow compared to sort of Computational experimentation. Like people are choosing like, I need something to hit. So people are going for hypotheses or ideas that are like, you know to use a sports an…”
Chan: CZ Biohub NY engineers immune cells to detect heart plaques
“And our New York biohub, we're doing cellular engineering to say like, Hey, can you go in to this person's heart? Check if they have plaques that are causing problems, read it into your DNA, self lice, And then we can read out the signal as cell-free DNA and g…”
Chan: CELLxGENE corpus reached 125M cells with 75% community contribution
“It took us about 10 years to get to a place where we had, we now have one of the largest corpus of RNA transcriptones, a hundred and twenty-five million cells. Cost a lot of money. And the really cool thing we discovered through that process was if we could se…”