Zuckerberg: Virtual cell modeling requires a hierarchical multi-scale architecture
Mark Zuckerberg · Priscilla Chan and Mark Zuckerberg: Frontier AI + Virtual Biology To Solve All Diseases · Nov 6, 2025 · at 13:11
Mark Zuckerberg explains CZI's computational roadmap for simulating complex biological systems with AI.
“I think like you want to kind of build up these models hierarchically so You give them a lot of data about specific proteins, and they can model specific proteins in the cells, and then you can model different cell behavior, and then eventually you get, you kind of zoom out and you're modeling like a virtual immune system or something like that, and it's sort of hard to simulate the immune system without having a good understanding of how a cell might work, and it's kind of hard to understand or simulate how a cell might work if you don't really understand how the proteins interact. So you kind of need systems that understand Data at all different levels of this, and then you kind of pull them together.”
quote is from the automated transcript, cleaned for reading: filler sounds and stutters are removed, nothing is rephrased. names can be misheard (the analysis reads context, assessments check outside sources). how →