The Ledger
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Sinclair: Time-Restricted Feeding Extended Mouse Lifespan by 30% Regardless of Diet
“And there's a very famous study that was done by a colleague of mine, Rafael de Cabo at the NIH in Bethesda, and he made three different types of diets for mice.
One that had a lot of protein, the other had carbs, the other had fat, and he thought he would fin…”
Sinclair: Slowing US Aging by One Year Saves $86 Trillion
“They calculated that the US alone, just by slowing down aging by one year, and making people productive, more productive for one year, would save over the next three decades, 86 trillion dollars, which we waste now on just keeping people alive in a sick state …”
Sinclair: NIH study found daily feeding windows extended mouse lifespans by 30%
“And there's a very famous study That was done by a colleague of mine, Rafael de Cabo at the NIH in Bethesda, and he made three different types of diets for mice. One that had a lot of protein, the other had carbs, the other had fat, and he thought he would fin…”
Sinclair: Recommended longevity habits add 14 to 15 years of life
“Just by doing the things that I'm talking about today, you'll get an extra 14, 15 years on average.”
Sinclair: Diabetics on Metformin Outlive Healthy Non-Diabetics
“By looking at type two diabetics, and there's a stunning, stunning fact, that type two diabetics that would normally have a short lifespan, when they take metformin, typically at two grams a day, I'm on one gram a day, by the way, they actually have less disea…”
Sinclair: Hip fracture mortality in elderly matches late-stage cancer
“The chances of dying after you break your hip as an older person is about as bad as late stage cancer.”
Sinclair: 80% of human longevity is lifestyle, only 20% is genetics
“80% of our longevity
And our health in the future is in our own hands.
Only 20% is genetic, which we cannot yet do much about.”
Sinclair: Olive Oil and Red Wine Compounds Activate Sirtuins to Improve Health
“And there are actually chemicals within those foods of a Mediterranean diet in olive oil and red wine. That we found in my lab to activate these sirtuins and probably also slow down the clock, but they certainly improve health.”