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Melas-Kyriazi: AI Back-Office Automation Will Drive Explosion of Small Businesses

John Milles-Kiriazzi · How AI Agents are Changing Investing · Joe Lonsdale · Apr 17, 2026 · at 34:17

Standard Metrics CEO John Milles-Kiriazzi and Joe Lonsdale discuss the macroeconomic impact of AI automation on labor and entrepreneurship.

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“I think what we're seeing now, which is really exciting is this explosion of small businesses getting started. And I think that people are going to be able to spend more time on what they're truly passionate about, probably spend more time on things that directly interface with other humans, whether it's producing products for them or working with them or helping them with something versus, you know, jobs that Were more about paper pushing that are going to become more automated.”

quote is from the automated transcript, cleaned for reading: filler sounds and stutters are removed, nothing is rephrased. names can be misheard (the analysis reads context, assessments check outside sources). how →

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