“You can't have an exponentiating cost curve without at least a following revenue curve.”
quote is from the automated transcript, cleaned for reading:
filler sounds and stutters are removed, nothing is rephrased. names can be misheard
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More from Reid Hoffman
Opinion
Hoffman: Silicon Valley's major blind spot is focusing strictly on software
“We have our kind of blind spots, and a classic one for us tends to be well, everything should be done in See us. Everything should be done in software. Everything should be done in bits.”
Reid HoffmanOct 20, 2025▶ 3:02Reid Hoffman on AI, Consciousness, and the Future of Labor
Insight
Hoffman: Predictive AI for drug discovery only needs 1% accuracy
“Simply doing prediction and getting that prediction right, and by the way, it doesn't have to be right a hundred percent of time, it has to be right, like, one percent of the time, because you can validate the other 99% were it right, and then finding that one…”
Reid HoffmanOct 20, 2025▶ 6:57Reid Hoffman on AI, Consciousness, and the Future of Labor
PredictionNot checkable as stated
Hoffman: Pure AI simulation will not solve drug discovery
“Silicon Valley will classically go, we'll put it all in simulation and that will solve it. Nope, that's not going to work.”
Reid HoffmanOct 20, 2025▶ 7:33Reid Hoffman on AI, Consciousness, and the Future of Labor
AssertionNot checkable as stated
Hoffman: AI models are better diagnostic knowledge stores than humans
“And so the diagnostic capabilities, these are much better knowledge stores than any human being on the planet.”
Reid HoffmanOct 20, 2025▶ 8:54Reid Hoffman on AI, Consciousness, and the Future of Labor
PredictionNot checkable as stated
Hoffman: In 10 to 20 years, doctors won't be human knowledge stores
“I actually think there will be a position for a doctor, 10 years from now, 20 years from now. It won't be as the knowledge store. It will be as a user of an, as an expert user of the knowledge store, but it's not gonna be, oh, because I went to med school for …”
Reid HoffmanOct 20, 2025▶ 9:17Reid Hoffman on AI, Consciousness, and the Future of Labor
PredictionNot checkable as stated
Hoffman: AI agency and goal-setting capabilities are almost certain
“I think agency and goals is almost certain. There is a question. I think this is one of the areas where we want to have some clarity and control. That was a little bit like the kind of question of what kind of compute fabric holds it together because you can't…”
Reid HoffmanOct 20, 2025▶ 31:45Reid Hoffman on AI, Consciousness, and the Future of Labor
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