Rapamycin

5 statements across 3 episodes · 5 bullish · 0 bearish · 2 people on the record · first statement Dec 23, 2018 by Kristen Fortney · said 9 times in 4 episodes since 2018 · across every show →

Mentions by year

brought up most by Kristen Fortney (7), Elad Gil (1), Dr. Eric Topol (1)

tap a year for its mentions
00214220182019202020212022202320242025episodesmentions
01220182019202020212022202320242025episodes it came up in
00214220182019202020212022202320242025episodesmentions per episode
2025 1 mention in 1 episode
2019 4 mentions in 2 episodes 2 per episode
2018 4 mentions in 1 episode

every mention, scene by scene, with the transcript →

Everything said about Rapamycin, oldest first

Dec 23, 2018 positive
Assertion Partly supported
Rapamycin reproducibly extends middle-aged mouse lifespan by 14% on average
“And this is, I would consider this to be one of the first drugs shown to reproducibly extend mouse lifespan. It's a very solid result. It's been done over and over again, and basically they gave this drug to mice starting from middle age, and it boosted their …”
Kristen Fortney Dec 23, 2018 ▶ 4:04 Extending Human Lifespan
Dec 23, 2018 bullish
Prediction Not checkable as stated
Current longevity clinical trials could add 10 to 20 healthy years
“Three different therapies are already in the clinic today. So as I mentioned, there are drugs targeting senescence, metformin, and there are drugs targeting rapamycin being tested in clinical trials now. And I think that could already add 10 to 20 years of hea…”
Kristen Fortney Dec 23, 2018 ▶ 10:28 Extending Human Lifespan
Dec 23, 2018 positive
Assertion Supported
Phase IIb trial shows rapamycin reduces elderly respiratory infections by 30%
“And they just published their Phase IIb data this summer, showing that Rapamycin can improve certain aspects of immunosenescence. So as you get older, your immune system doesn't work quite so well, and people who took rapamycin had 30% fewer respiratory infect…”
Kristen Fortney Dec 23, 2018 ▶ 4:46 Extending Human Lifespan
Jan 2, 2019 positive
Assertion Supported
Fortney: Rapamycin extended middle-aged mouse lifespan by 30 percent
“Even though they've only tested 30, there's already been one success rapamycin that came out of that, which is a very exciting discovery. Basically, the first molecule that came out of this large-scale program, they started to feed it to mice at middle age, an…”
Kristen Fortney Jan 2, 2019 ▶ 13:33 a16z Podcast | The Science Of Extending Life
Jan 2, 2019 positive
Assertion Partly supported
Gil: Rapamycin and metformin extend organism lifespans by 5% to 30%
“There's at least two FDA approved drugs that in multiple organisms will extend lifespan between five and 30%. One of them is rapamycin, which in mice, for example, extend lifespan 10 to 30%, and it also extends lifespan And flies and worms and other organisms.…”
Elad Gil Jan 2, 2019 ▶ 30:53 a16z Podcast | High Growth in Companies (and Tech)
Made with StarZero

Turn any episode into a week of clips.

This entire site, over 1,000 episodes transcribed, diarized, checked and made playable, runs on the StarZero media pipeline. Drop in your own episode and the podcast clipper finds the moments worth sharing, cuts them, captions them, and reframes them for every feed.