Dr. Linda Strauss is a clinical trial expert and co-founder of EI Ventures, discussing the strategic differences between the cannabis and psychedelic medical sectors.
“I see A lot more activity on the regulated pathway, whereas cannabis has clearly taken the adult use pathway with very few products that have moved into that space with Epidiolex being the exception to the rule.”
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More from Dr. Linda Strauss
Insight
Psilocybin breaks neural connections so follow-on psychotherapy can rewire them
“So if you think about a psychedelic trip, you can imagine that the psilocybin breaks apart those neural connections and then follow on psychotherapy Will reconnect them in a, air quote, healthier way.”
Dr. Linda StraussApr 28, 2022▶ 20:35Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
PredictionOpen · timeframe Apr 2027
The FDA will not approve psychedelic medicines without accompanying talk therapy
“I don't see the FDA, by the way, Sean, a hundred percent. I don't see the FDA approving any of this that isn't in combination with some form of talk therapy.”
Dr. Linda StraussApr 28, 2022▶ 27:32Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
AssertionSupported
Serious psilocybin side effects are linked to 5-HT receptor binding
“Now there is some side effects, serious side effects that have emerged with psilocybin due to its binding to the five HT The two B receptor. It's either the two A receptor, the two B receptor.”
Dr. Linda StraussApr 28, 2022▶ 23:15Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
AssertionSupported
Areas with cannabis dispensaries see lower rates of opioid use disorder
“There's a great study, I want to say it's out of UC Davis, that's literally shown a slightly different crisis, but the opioid overuse, you know, substance abuse diseases, an opioid use that's shown that in areas where there's cannabis dispensaries, there's a l…”
Dr. Linda StraussApr 28, 2022▶ 25:08Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
Disclosure
EI Ventures is developing a transdermal delivery patch for psilocybin
“In a press release, it's publicly announced that we are, at EI Ventures, are working with a contract research organization to develop a transdermal psilocybin patch, ultimately.”
Dr. Linda StraussApr 28, 2022▶ 11:22Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
AssertionSupported
Current antidepressant use is an exclusion criterion in psychedelic clinical trials
“Being on an antidepressant so far is an exclusionary criteria in probably all the clinical trials right now.”
Dr. Linda StraussApr 28, 2022▶ 22:45Psilocybin Breaks Neural Connections - Then Therapy Rewires Them
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