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Kian Sadeghi

Founder & CEO, Nucleus Genomics · 2 appearances on the record.

computed by AI from the episodes · how this works → · full disclaimer →

founderexecutive@KianSadeghi5 ↗LinkedIn ↗mynucleus.com ↗

After leaving the University of Pennsylvania in 2021, Sadeghi founded Nucleus Genomics and raised over $30 million to offer whole-genome health and embryo screening. He is known for promoting consumer access to genetic optimization, screening IVF embryos and adult genomes for polygenic disease risks and traits.

9statements → 3claims → 2claims resolved → 3.89/5average certainty → 2.44/5average debate potential → 8said about them ↓

2 supported 0 partly supported 0 contradicted 1 not checkable as stated how the 3 claims stand · each chip opens the sources

1 prediction · 2 assertions · 3 opinions · 3 disclosures · every statement was checked. The prediction and assertions are the 3 claims: statements the public record can support or contradict. 2 are resolved, and 1 names no date, number or outcome precise enough to check. Everything else (opinions, insights, what ifs, disclosures) can never be settled by the record, so it carries no assessment.

The record, in short

What the tape says about how Kian argues and how the claims held up. Everything they said, and everything said about them, is in the tabs below.

Their most notable supported claim

Assertion Supported
Sadeghi: 23andMe is not HIPAA compliant
“One of the most shocking things about 23 means is it's actually not HIPAA compliant, right? It doesn't follow the gold standard clinical regulations that ensure your data is safeguarded.”
Kian Sadeghi Mar 25, 2025 ▶ 3:30 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.

How they sound: not measured why? →

We measure speaking style by listening to the audio itself, and a fair number needs at least 2,000 words from one person on tape we have measured. There is too little of Kian Sadeghi on measured tape to publish a rate. This says nothing about how they speak.

Everything Kian Sadeghi said on TBPN that made the record, most notable first. Filter by type, assessment or year in the ledger →

Opinion
Sadeghi: 23andMe's genetic testing is ineffective for disease risk assessment
“Toilet meat technology missing millions and millions of genetic markers. Effectively, it's not actually useful for any really disease risk assessment.”
Kian Sadeghi Mar 25, 2025 ▶ 1:24 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Opinion
Sadeghi: 23andMe cannot develop drugs using microarray genetic data
“They really viewed data gathering as a means to make drugs, but because it's such a small sliver of your DNA, you actually can't really make drugs off of it”
Kian Sadeghi Mar 25, 2025 ▶ 3:02 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Assertion Supported
Sadeghi: 23andMe is not HIPAA compliant
“One of the most shocking things about 23 means is it's actually not HIPAA compliant, right? It doesn't follow the gold standard clinical regulations that ensure your data is safeguarded.”
Kian Sadeghi Mar 25, 2025 ▶ 3:30 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Prediction Not checkable as stated
Sadeghi predicts a whole-genome consumer health behemoth within a decade
“I really do think in the next decade, You're going to see the rise of a consumer health behemoth, and that consumer health behemoth is going to have a whole genome, the entire of someone's DNA at its foundation, and it's going to impact not just someone's heal…”
Kian Sadeghi Mar 25, 2025 ▶ 12:26 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Opinion
Sadeghi: Nucleus Genomics Is Years Ahead in Replacing 23andMe
“You go from Blockbuster to Netflix, you go from, you know, Blackberry to the iPhone, you go from MySpace to Facebook, and now you're going from 23 and Me to Nucleus Genomics, right? The industry is wide open, Nucleus is years ahead, and we're going to seize th…”
Kian Sadeghi Mar 25, 2025 ▶ 0:29 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Disclosure
Sadeghi: Nucleus Genomics is exploring an acquisition of 23andMe assets
“I think one thing this nucleus actively is looking into right now, considering whether it makes sense, you know, earlier, I'm sure you remember, you know, we explored the possibility of acquiring and we're looking into right now whether that would make sense t…”
Kian Sadeghi Mar 25, 2025 ▶ 5:39 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Assertion Supported
Sadeghi: Height has the best polygenic predictor in genomics today
“Even though the best predictor we have today, actually in the world, the best polygenic predictor is for height.”
Kian Sadeghi Jun 7, 2025 ▶ 50:22 Weekly Recap - Elon Vs Trump, Ukraine's Drone Attack, Cluely Update & OpenAI CRO
Disclosure
Nucleus plans platform expansion into blood, wearables, and full-body MRIs
“And then also we want to continue to build up that platform beyond just genetics, blood, wearables, URI analysis, full body MRIs, and beyond into a true consumer health application.”
Kian Sadeghi Mar 25, 2025 ▶ 8:43 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.
Disclosure
Sadeghi: Major Nucleus investors are inquiring about bidding on 23andMe
“Some of our big boy investors is in my, you know, they currently text me saying, what can we do here?”
Kian Sadeghi Mar 25, 2025 ▶ 14:49 Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics.

The other half of the tape: Kian Sadeghi's own voice is left out of every number here. Other people bring the name up 8 times in 2 episodes on TBPN. every mention, with the transcript →

Who brings them up most John Coogan 1

Every mention by year

tap a year for its mentions
0041822025episodesmentions
0122025episodes it came up in
0021422025episodesmentions per episode
2025 8 mentions in 2 episodes 4 per episode

Appearances (2)

EpisodeDateSpeaking time
Weekly Recap - Elon Vs Trump, Ukraine's Drone Attack, Cluely Update & OpenAI CRO Jun 7, 2025 6m
Kian Sadeghi on 23andMe’s Collapse and the Rise of Nucleus Genomics. Mar 25, 2025 9m
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