“Heart attacks are the number one cause of death. They're the number one cause of death in men and women. Cardiovascular disease deaths are the number one cause of death and total 40% more deaths than all cancers combined.”
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More from Dr. Jim
Insight
Not all arterial plaque is bad: stable plaque actually protects you
“We learned that not all plaque is bad. In fact, that some plaques are extremely dangerous for you and the strongest predictors of who will have a heart attack and others are actually Very stable and almost protected against having a heart attack in the future.”
Dr. JimApr 14, 2025▶ 7:37He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
AssertionSupported
The first symptom of heart disease is often a catastrophic event
“The most common presentation for having heart disease like that is not presenting with chest pain or shortness of breath, but it's simply having a catastrophic event, dying of a heart attack or suffering a heart attack at home with no antecedent warning.”
Dr. JimApr 14, 2025▶ 3:40He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
AssertionSupported
90% of heart attacks are preventable with existing medical treatments
“90% of heart attacks are preventable. We, it's not that we lack the treatments. It's that we're just not identifying people soon enough so that we can prevent these events from happening.”
Dr. JimApr 14, 2025▶ 4:11He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
AssertionSupported
Heart medications don't eliminate plaque; they transform it into stable protective plaque
“And what we found was that the medicines, they didn't make plaque go away per se. They just transformed that plaque from the good to the, from the bad to the good plaque over time, and that was the mechanism of stabilization.”
Dr. JimApr 14, 2025▶ 8:12He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
Disclosure
Cleerly is running a 7,500-patient RCT on asymptomatic screening
“We're doing a large-scale randomized control trial right now. It's about 7500 patients. We're a little over 2000 patients enrolled, and the purpose of this trial is to test the hypothesis that image-guided care, clearly guided care, is superior to conventional…”
Dr. JimApr 14, 2025▶ 25:55He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
Disclosure
Cleerly's massive clinical trial costs well over $200 million
“Like, if you include the in-kind support, like, it's well over two hundred million dollars to do this trial.”
Dr. JimApr 14, 2025▶ 32:26He raised $300M to prevent heart attacks. Here's how he got his health tech startup off the groun... · PMF Show
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