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Goodarzi: Cell state AI is data-limited, unlike compute-constrained DNA models

Hani Goodarzi · No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute · Feb 25, 2025 · at 6:28

Hani Goodarzi, Core Investigator at the Arc Institute, explains the differing bottlenecks between training AI on genomic sequences versus cellular states.

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“When it comes to, for example, DNA language models, again, thanks to the field and decades of having sequenced a ton of genomes we are not as much data limited, but Compute and specifically context and how long we can actually consume DNA and what size of inputs and all of that is actually a big limitation that we have tried to solve. But when it comes to kind of cell estate models that is an area that we are absolutely very much data limited”

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