quote is from the automated transcript, cleaned for reading:
filler sounds and stutters are removed, nothing is rephrased. names can be misheard
(the analysis reads context, assessments check outside sources). how →
More from Surya Ganguli
Insight
Ganguli: Specialized Models Beat Fine-Tuned Foundation Models for Specific Tasks
“You really, I think you're best off with a specialized model trained on the data that's very relevant to the thing, the task you want to solve. Your second best bet is to start with a foundation model that understands the broad space and fine tune it. Again, o…”
Surya GanguliOct 3, 2024▶ 16:11AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
AssertionSupported
Ganguli: FDA-approved drugs target only 800 of roughly 20,000 human genes
“FDA approved drugs they target only 800 of the 20,000 known genes that we have, 20 to 25,000 known genes that we have.”
Surya GanguliOct 3, 2024▶ 11:01AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
Insight
Ganguli: Evolutionary robustness proves low-dimensional structure controls biological function
“Biological systems have survived for almost four billion years of evolution. They've tolerated all sorts of insults, competition, and so forth, so they're extremely robust. Because they're robust, their function can't depend on all of the details. That means t…”
Surya GanguliOct 3, 2024▶ 21:53AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
Insight
Ganguli: ESMFold proves language models can learn protein structure from sequences
“I was actually really impressed by ESM fold, this average scale modeling where you could kind of do the same thing that you do for language, but do it for sequences. And then you learn representations that know about the structure of proteins.”
Surya GanguliOct 3, 2024▶ 0:47AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
AssertionSupported
Ganguli: ESM-3 model trained on 2.8 billion amino acid sequences
“ESM-III with evolutionary scale modeling did the same language modeling, but now on amino acid sequences of about 2.8 billion sequences, right?”
Surya GanguliOct 3, 2024▶ 5:02AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
AssertionSupported
Ganguli: Bringing a drug to market costs $2.5B and takes 10–15 years
“The cost of drug design, I mean, I know in the industry this is well known, but it's worth, worth emphasizing, it's 2.5 billion dollars per drug in 10 to 15 years, right?”
Surya GanguliOct 3, 2024▶ 10:33AI at the Intersection of Bio | Vijay Pande, Surya Ganguli & Bowen Liu
Made with StarZero
Turn any episode into a week of clips.
This entire site, over 1,000 episodes transcribed, diarized, checked and made playable,
runs on the StarZero media pipeline. Drop in your own episode and the podcast clipper finds the
moments worth sharing, cuts them, captions them, and reframes them for every feed.
We use essential cookies to make the site work. With your permission we
also use analytics cookies (Google Analytics and Mixpanel) to understand
usage and improve StarZero. See our Cookie Policy.