Jan 2, 2019 · 44m · a16z

a16z Podcast | Quantum Leap

Ilyas Khan · 32m spoken Sonal Chokshi · 4m spoken
0:00 / 0:00
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In this episode of the a16z podcast, guest Ilyas Khan, founder and CEO of Cambridge Quantum Computing, demystifies the current state and realistic potential of quantum technology. He explores the shift from academic theory to commercial hardware and software development, the physics behind quantum advantage, near-term business applications, and the broader societal and philosophical implications of quantum mechanics.

How this conversation actually went

Every chapter scored 0–10 on four independent dynamics. Hover any point for the reasoning behind the score. The host holds 10.8% of the talking time here. How this is scored →

The host as informed peer 3.2 Guest teaching 4.4 Guest disagreement 1.6 The host pushing back 2.2
05100:0015:0030:001:15–7:58 · The host as informed peer 2/10 History and Global Investment Landscape The host opens with broad exploratory questions regarding quantum computing promises and current key players. Khan provides an extensive historical overview from Feynman to modern geopolitical and corporate investments, gently correcting Sonal's doubt about US government funding.7:58–15:37 · The host as informed peer 3/10 Quantum Mechanics, Entanglement, and Encryption Sonal asks about practical applications beyond gate logic, and Khan acknowledges current uncertainty using a mobile phone history analogy. Khan educates the hosts on quantum entanglement and quantum key encryption, clarifying Sonal's question about speed versus fundamental primitives.15:37–20:14 · The host as informed peer 3/10 Strategic Applications and Optimization Problems The host questions why profit-driven companies are investing if practical applications remain unknown. Khan clarifies his earlier statement and outlines concrete strategic applications in defense, genomics, and predictive financial modeling.20:14–23:10 · The host as informed peer 4/10 Quantum Computing vs. Classical Supercomputers Sonal asks a provocative question, suggesting quantum computing might be an academic tech seeking a problem that classical simulations could solve. Khan vigorously refutes this, explaining that mathematical limits make classical factorization impossible regardless of supercomputer scale.23:10–25:47 · The host as informed peer 3/10 Power Distribution and Corporate R&D Dominance The host raises ethical and market distribution concerns about corporate dominance over quantum technology. Khan outlines the historical pattern of technology monopolies and highlights how corporate R&D budgets have surpassed university research.25:47–28:40 · The host as informed peer 4/10 The Role of Startups in Quantum Software Sonal frames a well-informed question comparing quantum startup opportunities to the AWS-driven software explosion. Khan explains that hardware is exclusive to tech giants, whereas startups will dominate algorithm development.28:40–31:29 · The host as informed peer 2/10 Cambridge Quantum Computing Origin and Strategy The host asks if Cambridge Quantum Computing is essentially creating an OS. Khan elaborates on the company's origin, their algorithmic strategy, and how Google's UCSB acquisition shifted their timeline.31:29–33:36 · The host as informed peer 5/10 University IP Models and the Cambridge Ecosystem Sonal demonstrates detailed knowledge of tech transfer models, contrasting Stanford's open IP approach with traditional university frameworks. Khan enthusiastically agrees with Sonal's critique and shares his experience funding Cambridge accelerators.33:36–37:36 · The host as informed peer 4/10 Programming Challenges and Bare Metal Development The host draws a smart analogy to multi-core processing where hardware outpaces software. Khan enthusiastically expands on this, explaining that quantum software currently requires theoretical mathematicians and Fields Medalists rather than standard software engineers.37:36–41:12 · The host as informed peer 2/10 Philosophy of Mathematics and Theoretical Physics The host asks how Khan's work in quantum computing intersects with his passion for philosophy of mathematics. Khan shares insights on Wittgenstein, the limits of language, and his involvement with Stephen Hawking.41:12–44:04 · The host as informed peer 3/10 Future of Education, STEM, and Product Philosophy Sonal notes the irony that Khan advocates strongly for STEM education while personally embodying a multidisciplinary blend of philosophy and arts. Khan clarifies his belief that optimal engineering conceals underlying complexity from users.1:15–7:58 · Guest teaching 4/10 History and Global Investment Landscape The host opens with broad exploratory questions regarding quantum computing promises and current key players. Khan provides an extensive historical overview from Feynman to modern geopolitical and corporate investments, gently correcting Sonal's doubt about US government funding.7:58–15:37 · Guest teaching 5/10 Quantum Mechanics, Entanglement, and Encryption Sonal asks about practical applications beyond gate logic, and Khan acknowledges current uncertainty using a mobile phone history analogy. Khan educates the hosts on quantum entanglement and quantum key encryption, clarifying Sonal's question about speed versus fundamental primitives.15:37–20:14 · Guest teaching 5/10 Strategic Applications and Optimization Problems The host questions why profit-driven companies are investing if practical applications remain unknown. Khan clarifies his earlier statement and outlines concrete strategic applications in defense, genomics, and predictive financial modeling.20:14–23:10 · Guest teaching 6/10 Quantum Computing vs. Classical Supercomputers Sonal asks a provocative question, suggesting quantum computing might be an academic tech seeking a problem that classical simulations could solve. Khan vigorously refutes this, explaining that mathematical limits make classical factorization impossible regardless of supercomputer scale.23:10–25:47 · Guest teaching 5/10 Power Distribution and Corporate R&D Dominance The host raises ethical and market distribution concerns about corporate dominance over quantum technology. Khan outlines the historical pattern of technology monopolies and highlights how corporate R&D budgets have surpassed university research.25:47–28:40 · Guest teaching 4/10 The Role of Startups in Quantum Software Sonal frames a well-informed question comparing quantum startup opportunities to the AWS-driven software explosion. Khan explains that hardware is exclusive to tech giants, whereas startups will dominate algorithm development.28:40–31:29 · Guest teaching 4/10 Cambridge Quantum Computing Origin and Strategy The host asks if Cambridge Quantum Computing is essentially creating an OS. Khan elaborates on the company's origin, their algorithmic strategy, and how Google's UCSB acquisition shifted their timeline.31:29–33:36 · Guest teaching 3/10 University IP Models and the Cambridge Ecosystem Sonal demonstrates detailed knowledge of tech transfer models, contrasting Stanford's open IP approach with traditional university frameworks. Khan enthusiastically agrees with Sonal's critique and shares his experience funding Cambridge accelerators.33:36–37:36 · Guest teaching 5/10 Programming Challenges and Bare Metal Development The host draws a smart analogy to multi-core processing where hardware outpaces software. Khan enthusiastically expands on this, explaining that quantum software currently requires theoretical mathematicians and Fields Medalists rather than standard software engineers.37:36–41:12 · Guest teaching 4/10 Philosophy of Mathematics and Theoretical Physics The host asks how Khan's work in quantum computing intersects with his passion for philosophy of mathematics. Khan shares insights on Wittgenstein, the limits of language, and his involvement with Stephen Hawking.41:12–44:04 · Guest teaching 3/10 Future of Education, STEM, and Product Philosophy Sonal notes the irony that Khan advocates strongly for STEM education while personally embodying a multidisciplinary blend of philosophy and arts. Khan clarifies his belief that optimal engineering conceals underlying complexity from users.1:15–7:58 · Guest disagreement 1/10 History and Global Investment Landscape The host opens with broad exploratory questions regarding quantum computing promises and current key players. Khan provides an extensive historical overview from Feynman to modern geopolitical and corporate investments, gently correcting Sonal's doubt about US government funding.7:58–15:37 · Guest disagreement 2/10 Quantum Mechanics, Entanglement, and Encryption Sonal asks about practical applications beyond gate logic, and Khan acknowledges current uncertainty using a mobile phone history analogy. Khan educates the hosts on quantum entanglement and quantum key encryption, clarifying Sonal's question about speed versus fundamental primitives.15:37–20:14 · Guest disagreement 2/10 Strategic Applications and Optimization Problems The host questions why profit-driven companies are investing if practical applications remain unknown. Khan clarifies his earlier statement and outlines concrete strategic applications in defense, genomics, and predictive financial modeling.20:14–23:10 · Guest disagreement 3/10 Quantum Computing vs. Classical Supercomputers Sonal asks a provocative question, suggesting quantum computing might be an academic tech seeking a problem that classical simulations could solve. Khan vigorously refutes this, explaining that mathematical limits make classical factorization impossible regardless of supercomputer scale.23:10–25:47 · Guest disagreement 1/10 Power Distribution and Corporate R&D Dominance The host raises ethical and market distribution concerns about corporate dominance over quantum technology. Khan outlines the historical pattern of technology monopolies and highlights how corporate R&D budgets have surpassed university research.25:47–28:40 · Guest disagreement 1/10 The Role of Startups in Quantum Software Sonal frames a well-informed question comparing quantum startup opportunities to the AWS-driven software explosion. Khan explains that hardware is exclusive to tech giants, whereas startups will dominate algorithm development.28:40–31:29 · Guest disagreement 1/10 Cambridge Quantum Computing Origin and Strategy The host asks if Cambridge Quantum Computing is essentially creating an OS. Khan elaborates on the company's origin, their algorithmic strategy, and how Google's UCSB acquisition shifted their timeline.31:29–33:36 · Guest disagreement 1/10 University IP Models and the Cambridge Ecosystem Sonal demonstrates detailed knowledge of tech transfer models, contrasting Stanford's open IP approach with traditional university frameworks. Khan enthusiastically agrees with Sonal's critique and shares his experience funding Cambridge accelerators.33:36–37:36 · Guest disagreement 2/10 Programming Challenges and Bare Metal Development The host draws a smart analogy to multi-core processing where hardware outpaces software. Khan enthusiastically expands on this, explaining that quantum software currently requires theoretical mathematicians and Fields Medalists rather than standard software engineers.37:36–41:12 · Guest disagreement 1/10 Philosophy of Mathematics and Theoretical Physics The host asks how Khan's work in quantum computing intersects with his passion for philosophy of mathematics. Khan shares insights on Wittgenstein, the limits of language, and his involvement with Stephen Hawking.41:12–44:04 · Guest disagreement 2/10 Future of Education, STEM, and Product Philosophy Sonal notes the irony that Khan advocates strongly for STEM education while personally embodying a multidisciplinary blend of philosophy and arts. Khan clarifies his belief that optimal engineering conceals underlying complexity from users.1:15–7:58 · The host pushing back 1/10 History and Global Investment Landscape The host opens with broad exploratory questions regarding quantum computing promises and current key players. Khan provides an extensive historical overview from Feynman to modern geopolitical and corporate investments, gently correcting Sonal's doubt about US government funding.7:58–15:37 · The host pushing back 2/10 Quantum Mechanics, Entanglement, and Encryption Sonal asks about practical applications beyond gate logic, and Khan acknowledges current uncertainty using a mobile phone history analogy. Khan educates the hosts on quantum entanglement and quantum key encryption, clarifying Sonal's question about speed versus fundamental primitives.15:37–20:14 · The host pushing back 3/10 Strategic Applications and Optimization Problems The host questions why profit-driven companies are investing if practical applications remain unknown. Khan clarifies his earlier statement and outlines concrete strategic applications in defense, genomics, and predictive financial modeling.20:14–23:10 · The host pushing back 5/10 Quantum Computing vs. Classical Supercomputers Sonal asks a provocative question, suggesting quantum computing might be an academic tech seeking a problem that classical simulations could solve. Khan vigorously refutes this, explaining that mathematical limits make classical factorization impossible regardless of supercomputer scale.23:10–25:47 · The host pushing back 2/10 Power Distribution and Corporate R&D Dominance The host raises ethical and market distribution concerns about corporate dominance over quantum technology. Khan outlines the historical pattern of technology monopolies and highlights how corporate R&D budgets have surpassed university research.25:47–28:40 · The host pushing back 2/10 The Role of Startups in Quantum Software Sonal frames a well-informed question comparing quantum startup opportunities to the AWS-driven software explosion. Khan explains that hardware is exclusive to tech giants, whereas startups will dominate algorithm development.28:40–31:29 · The host pushing back 1/10 Cambridge Quantum Computing Origin and Strategy The host asks if Cambridge Quantum Computing is essentially creating an OS. Khan elaborates on the company's origin, their algorithmic strategy, and how Google's UCSB acquisition shifted their timeline.31:29–33:36 · The host pushing back 3/10 University IP Models and the Cambridge Ecosystem Sonal demonstrates detailed knowledge of tech transfer models, contrasting Stanford's open IP approach with traditional university frameworks. Khan enthusiastically agrees with Sonal's critique and shares his experience funding Cambridge accelerators.33:36–37:36 · The host pushing back 2/10 Programming Challenges and Bare Metal Development The host draws a smart analogy to multi-core processing where hardware outpaces software. Khan enthusiastically expands on this, explaining that quantum software currently requires theoretical mathematicians and Fields Medalists rather than standard software engineers.37:36–41:12 · The host pushing back 1/10 Philosophy of Mathematics and Theoretical Physics The host asks how Khan's work in quantum computing intersects with his passion for philosophy of mathematics. Khan shares insights on Wittgenstein, the limits of language, and his involvement with Stephen Hawking.41:12–44:04 · The host pushing back 2/10 Future of Education, STEM, and Product Philosophy Sonal notes the irony that Khan advocates strongly for STEM education while personally embodying a multidisciplinary blend of philosophy and arts. Khan clarifies his belief that optimal engineering conceals underlying complexity from users.

speaking balance: gold is the host, purple is the guest (3 minute bins)

0:00 · the host 0% · guest 100%0:00 · the host 0% · guest 100%3:00 · the host 2.6% · guest 97.4%3:00 · the host 2.6% · guest 97.4%6:00 · the host 16.2% · guest 83.8%6:00 · the host 16.2% · guest 83.8%9:00 · the host 18.2% · guest 81.8%9:00 · the host 18.2% · guest 81.8%12:00 · the host 2.6% · guest 97.4%12:00 · the host 2.6% · guest 97.4%15:00 · the host 0.8% · guest 99.2%15:00 · the host 0.8% · guest 99.2%18:00 · the host 20.2% · guest 79.8%18:00 · the host 20.2% · guest 79.8%21:00 · the host 1.7% · guest 98.3%21:00 · the host 1.7% · guest 98.3%24:00 · the host 32.4% · guest 67.6%24:00 · the host 32.4% · guest 67.6%27:00 · the host 0.4% · guest 99.6%27:00 · the host 0.4% · guest 99.6%30:00 · the host 21.5% · guest 78.5%30:00 · the host 21.5% · guest 78.5%33:00 · the host 9.3% · guest 90.7%33:00 · the host 9.3% · guest 90.7%36:00 · the host 12% · guest 88%36:00 · the host 12% · guest 88%39:00 · the host 13% · guest 87%39:00 · the host 13% · guest 87%42:00 · the host 10.2% · guest 89.8%42:00 · the host 10.2% · guest 89.8%
Sharpest disagreement ▶ 20:43 Rejecting Academic Tech Premise

Khan firmly rejects Sonal's suggestion that quantum computing is an academic solution in search of a problem, pointing out that classical supercomputers mathematically cannot break factorization.

Hardest push from the host ▶ 20:22 Sonal's Blasphemous Question

Sonal directly challenges the core premise of the episode by asking if quantum computing is merely an academic pursuit that existing classical simulations can already solve.

Biggest teaching moment ▶ 20:43 Fundamental Limits of Classical Computing

Khan educates the host on why quantum computing represents a difference of kind rather than degree, demonstrating that classical systems are mathematically incapable of handling certain class problems regardless of scale.

The host holds their own ▶ 31:26 Stanford IP Model Analysis

Sonal showcases deep expertise in startup ecosystems and tech transfer dynamics by detailing how Stanford's IP model creates long-term ecosystem value compared to traditional university approaches.

the scores for every segment, with the reasoning behind each
ChapterTopicThe host as informed peerGuest teachingGuest disagreementThe host pushing backWhy
History and Global Investment Landscape 2411 The host opens with broad exploratory questions regarding quantum computing promises and current key players. Khan provides an extensive historical overview from Feynman to modern geopolitical and corporate investments, gently correcting Sonal's doubt about US government funding.
Quantum Mechanics, Entanglement, and Encryption 3522 Sonal asks about practical applications beyond gate logic, and Khan acknowledges current uncertainty using a mobile phone history analogy. Khan educates the hosts on quantum entanglement and quantum key encryption, clarifying Sonal's question about speed versus fundamental primitives.
Strategic Applications and Optimization Problems 3523 The host questions why profit-driven companies are investing if practical applications remain unknown. Khan clarifies his earlier statement and outlines concrete strategic applications in defense, genomics, and predictive financial modeling.
Quantum Computing vs. Classical Supercomputers 4635 Sonal asks a provocative question, suggesting quantum computing might be an academic tech seeking a problem that classical simulations could solve. Khan vigorously refutes this, explaining that mathematical limits make classical factorization impossible regardless of supercomputer scale.
Power Distribution and Corporate R&D Dominance 3512 The host raises ethical and market distribution concerns about corporate dominance over quantum technology. Khan outlines the historical pattern of technology monopolies and highlights how corporate R&D budgets have surpassed university research.
The Role of Startups in Quantum Software 4412 Sonal frames a well-informed question comparing quantum startup opportunities to the AWS-driven software explosion. Khan explains that hardware is exclusive to tech giants, whereas startups will dominate algorithm development.
Cambridge Quantum Computing Origin and Strategy 2411 The host asks if Cambridge Quantum Computing is essentially creating an OS. Khan elaborates on the company's origin, their algorithmic strategy, and how Google's UCSB acquisition shifted their timeline.
University IP Models and the Cambridge Ecosystem 5313 Sonal demonstrates detailed knowledge of tech transfer models, contrasting Stanford's open IP approach with traditional university frameworks. Khan enthusiastically agrees with Sonal's critique and shares his experience funding Cambridge accelerators.
Programming Challenges and Bare Metal Development 4522 The host draws a smart analogy to multi-core processing where hardware outpaces software. Khan enthusiastically expands on this, explaining that quantum software currently requires theoretical mathematicians and Fields Medalists rather than standard software engineers.
Philosophy of Mathematics and Theoretical Physics 2411 The host asks how Khan's work in quantum computing intersects with his passion for philosophy of mathematics. Khan shares insights on Wittgenstein, the limits of language, and his involvement with Stephen Hawking.
Future of Education, STEM, and Product Philosophy 3322 Sonal notes the irony that Khan advocates strongly for STEM education while personally embodying a multidisciplinary blend of philosophy and arts. Khan clarifies his belief that optimal engineering conceals underlying complexity from users.

Statements from this episode (15)

Assertion Not checkable as stated
Corporate quantum computing research surpassed academic work around 2018
“The tipping point occurred late last year when the work being done by corporate entities, which have a profit motive, became more important than the work that was being done by academia.”
Ilyas Khan Jan 2, 2019 ▶ 3:19
Assertion Not checkable as stated
China made quantum computing its top national priority with unlimited budget
“As far as the Chinese were concerned, quantum computing is their number one priority. It's not water. It's not population controlled. It's not food. It is quantum computing. There is no budget. Which means there's no limit to the budget. It means not that ther…”
Ilyas Khan Jan 2, 2019 ▶ 5:04
Prediction Not checkable as stated
Quantum computing will impact society more than the Industrial Revolution
“If the promise that Feynman held forth in the early eighties is even remotely true, then the impact of quantum computing on our lives as we sit around this table will be greater, for example, than that That our forefathers during the industrial revolution had …”
Ilyas Khan Jan 2, 2019 ▶ 6:26
Assertion Not checkable as stated
Quantum computers will solve optimization problems thousands of times faster
“For example, the thousands of years that it might take current computers to solve a certain optimization problem could be done very quickly.”
Ilyas Khan Jan 2, 2019 ▶ 10:49
Assertion Open · timeframe Nov 2020
Quantum computing will render standard public key encryption obsolete
“The current state of affairs is that when we communicate, more often than not, the public key encryption that we use is based on the inability of computers to find factors for large numbers. And so breaking or creating codes will no longer be possible using th…”
Ilyas Khan Jan 2, 2019 ▶ 11:23
Assertion Partly supported
A 50-qubit quantum computer outpowers any existing classical supercomputer
“And a quantum computer, even with a modest number of qubits, and the analogy that gets banded around by everybody who's been on the D-Wave website, or who's read all these articles, Is that a Quantum computer with 40 or 50 entangled qubits would be more powerf…”
Ilyas Khan Jan 2, 2019 ▶ 18:31
Prediction Not checkable as stated
Quantum computing will unlock rapid DNA analysis and custom designer drugs
“We're not there yet, by the way, but when we get there, these machines will have an amazing capacity to solve these types of problems. One of the applications from that would be the quick and careful analysis of our DNA, and the creation of designer drugs.”
Ilyas Khan Jan 2, 2019 ▶ 18:59
Assertion Not checkable as stated
Precision engineering enables physical quantum computing beyond academic theory
“The reason why it's no longer academic is that the advances in engineering, the same reason why we have the Large Hadron Collider, the same reason we have well, there's so many advances in engineering, of course, now, because the, I think the gate fidelity of …”
Ilyas Khan Jan 2, 2019 ▶ 22:36
Prediction Not checkable as stated
The greatest fortunes in quantum computing will be made in software
“Now, I'm not on the hardware side. My, I, I'm on a different side of the business, which I find much more fascinating and where I think the great fortunes are going to be made.”
Ilyas Khan Jan 2, 2019 ▶ 25:21
Opinion
Building quantum computing hardware is not a game for early-stage startups
“First of all, I think that the big hardware game is absolutely not startup. The people that have got the resources to be able to attack this problem are, by definition, the big guys.”
Ilyas Khan Jan 2, 2019 ▶ 26:47
Opinion
D-Wave's pioneering machine is not a true quantum computer
“I'm one of those that, that admire the pioneering work that D-Wave have done, although I don't think their machine is a true quantum computer.”
Ilyas Khan Jan 2, 2019 ▶ 27:13
Assertion Supported
Google entered quantum computing by acquiring UC Santa Barbara's research team
“Easter last year, 2014, was when everything changed. Everything changed. It was when Google disclosed the fact that they were so heavily involved. They went and bought the University of California, Santa Barbara team.”
Ilyas Khan Jan 2, 2019 ▶ 30:19
Assertion Partly supported
Microsoft hires Fields Medalists over traditional coders for topological quantum computing
“So if you look at Microsoft, this topological Cubit, you know, the program that they're doing, they've got Fields Medal winners taken away from the blackboards. Not people who code.”
Ilyas Khan Jan 2, 2019 ▶ 35:54
Prediction Not checkable as stated
Quantum software developers will work closely with hardware in coming years
“I can see that software expertise, people that are just magnificent and equipped to create the sorts of products that we've been talking about, they will work more closely with initially the hardware than has been the case for a very long time.”
Ilyas Khan Jan 2, 2019 ▶ 36:56
Opinion
Unifying quantum mechanics and relativity is humanity's greatest prize
“I cannot think of a greater prize for humanity than making progress in unifying these approaches, and thereby understanding the essential question that we've always asked, which is, how did it all happen?”
Ilyas Khan Jan 2, 2019 ▶ 39:54
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