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Isenberg defines skills, sub-agents, and MCPs in agent architecture

Greg Isenberg · OpenAI Releases ChatGPT AI Agent Skills · Dec 22, 2025 · at 2:20

Greg Isenberg breaks down the functional architectural differences between agent skills, sub-agents, and Model Context Protocol (MCP) integrations.

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“A skill is like a written guide that tells, you know, Claude or You know, Codex or ChatGPT exactly how to do a specific task. For example, analyze spreadsheets this way, or write emails in this voice, or design you know, design the interface like this. So you can basically call and reuse the same skill again and it just, it allows for more consistent output. So what is a sub-agent? Well, a sub-agent is making a few extra copies Of, you know, the LLM that you're using, you know, Claude or Codex or ChatGPT, each with its own job, such as you review the code, you write tests, you update docs. The main LLM can hand out pieces of a big task to help these workers. So work happens in parallel and stays organized. And an MCP is just a universal power plug that lets the LLM access other tools.”

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