The Ledger

Every statement that passed quotation and attribution checks. Mix any filter with any other: certainty 1/5, debate potential 5/5, or both at once.

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why aren't all 37 resolved? a statement only gets an assessment when the public record can support or contradict it. opinions and what-ifs never can, and 0 checkable ones are still open, waiting for their date. predictions held up or didn't; assertions are supported or contradicted. on every card: ▮▮▮▮▮ certainty · ▮▮▮▮▮ debate potential. speakers are clickable

Prediction Not checkable as stated
Pesenti: AI matching human intelligence is at least 20-30 years away
“And I don't believe anybody has a good view as to when will match human intelligence, but it's not going to happen in the next decade, not going to happen in the next two or three decades. It's going to take much longer.”
Jerome Pesenti Jun 10, 2020 ▶ 36:29 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Not checkable as stated
Pesenti in 2020: AI will not become accessible to non-programmers anytime soon
“I don't buy that AI will be accessible to people who don't have a programming background anytime soon, right? So, but it will be part of, you know, machine learning will be part of the tool set of Any programmers, but it would still be, you know, for kind of m…”
Jerome Pesenti Jun 10, 2020 ▶ 53:37 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Not checkable as stated
Pesenti: Deepfake detection will never be a solved problem
“It's never going to be a soft problem, right? So it's always going to be an arm race. I'm confident that we can actually identify part of it. I think we can act on it. We can label it in the case where it matters to users, but I'm also confident that it's goin…”
Jerome Pesenti Jun 10, 2020 ▶ 12:42 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Not checkable as stated
Pesenti: AI will not enter another winter anytime soon
“In my opinion, you know, we're not going to go to any AI winter anytime soon.”
Jerome Pesenti Jun 10, 2020 ▶ 24:29 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Opinion
Pesenti in 2020: Large neural chatbots are not ready for consumer products
“It's not ready for prime consumption, let's be clear. You know, like these bots have lots of interesting side effects. You know, you cannot really control what they're gonna say. But they are quite entertaining, quite engaging, and a lot more human-like than y…”
Jerome Pesenti Jun 10, 2020 ▶ 29:30 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Held up
Pesenti in 2020: 10x annual AI compute scaling is economically unsustainable
“So we're still pushing hard, but it's not going to be 10 X per year. It's just not sustainable.”
Jerome Pesenti Jun 10, 2020 ▶ 33:40 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Supported
Pesenti in 2020: Multi-million-dollar AI training runs are unsustainable for Facebook
“Where it becomes millions is when you do training runs. So some of the training runs in the most advanced system that it comes from our company or other companies out there are starting to be extremely expensive. Yeah. Like you can look at one run in the scale…”
Jerome Pesenti Jun 10, 2020 ▶ 34:56 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Insight
Pesenti: General intelligence does not exist, as human intelligence is domain-specific
“Human intelligence is no, it's not general. It's actually very, very specific to our world. It's very biased. It's really customized to survival human in, on our planet. So the concept of general intelligence, I mean, yes, humans tend to have a more general in…”
Jerome Pesenti Jun 10, 2020 ▶ 36:58 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Not checkable as stated
Pesenti: Self-supervised learning will supersede other AI techniques across fields
“Self-supervised learning is really showing promises everywhere, you know, so it's obviously that's the technique behind large language models, but our, you know, my team came up with new papers around vision. So we believe actually that these techniques will s…”
Jerome Pesenti Jun 10, 2020 ▶ 51:48 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
Two AI-generated ALS compounds outperformed standard-of-care treatments in lab validation
“We actually put the five hypothesis in the lab, and at this point, it's in vitro and in vivo validation, and, you know, two of them didn't work well one of them work as well as this kind of standard of care at the moment, and two of them work actually much bet…”
Jerome Pesenti Oct 26, 2017 ▶ 17:42 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Assertion Contradicted
Pesenti: Facebook employs 30,000 content moderators
“So we have actually 30,000 moderators that try to really understand if the content that's published on a platform satisfy our policy, but 30,000, given the number, the amount of content, and you're talking about billions of pieces of content every day is not e…”
Jerome Pesenti Jun 10, 2020 ▶ 6:01 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Partly supported
Pesenti in 2020: 9B parameter Blenderbot is the largest chat model
“It's the largest chat model out there. It's nine billion parameters.”
Jerome Pesenti Jun 10, 2020 ▶ 28:02 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Disclosure
Pesenti: Inference remains Facebook's largest machine learning cost
“Actually, To be clear, the most costly thing we do in ML is still inference cost, because when you put a piece of content within Facebook, it's running hundreds of different ML based algorithm, and they all run on machine parallel, and it's using a huge number…”
Jerome Pesenti Jun 10, 2020 ▶ 34:33 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Supported
Pesenti: Facebook AI transformer models matched or beat Mathematica at math
“My team also applied transformer models to mathematics, you know, doing, like, things like partial derivation equation or integration and showing that, hey, it could work as well better than Mathematica or some, you know, hundred page long algorithm.”
Jerome Pesenti Jun 10, 2020 ▶ 40:49 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Disclosure
Pesenti: Facebook is going end-to-end all-in on PyTorch
“We're definitely going all in as PyTorch, you know, end to end. So I think initially when we launched the Onyx strategy, it was more like a multi-framework world. And we had actually two framework internally between PyTorch and Cafe Two, but we're still suppor…”
Jerome Pesenti Jun 10, 2020 ▶ 55:46 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
The overall cost of scientific discovery may be increasing exponentially
“Because the number of researchers is almost increasing exponentially, but our growth rate actually is kind of almost decreasing, it may be true not just for drugs, but, you know, overall for humanity that the cost of discovery is increasing exponentially.”
Jerome Pesenti Oct 26, 2017 ▶ 0:43 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Disclosure
BenevolentAI has initiated a Phase II clinical trial
“We actually started just now. A clinical trial phase two, so we're going all the way from, ah, the AI to the actual clinical trials.”
Jerome Pesenti Oct 26, 2017 ▶ 3:05 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Opinion
Chemists consider molecules from published AI generative chemistry models impractical
“Now there are lots of great papers that have been written around using machine learning and neural network around generating new chemistry, but if you really look at them, if you actually get chemists to look at what's generated, they will say, ah, that's a jo…”
Jerome Pesenti Oct 26, 2017 ▶ 15:44 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Insight
Large pharma relies on acquisitions rather than internal drug research
“Large pharma is not really the research engine anymore, and that a lot of the large pharma actually will acquire more than develop themselves.”
Jerome Pesenti Oct 26, 2017 ▶ 19:58 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Insight
Large pharma incentives encourage researchers to push failing programs to completion
“If you're in a large pharma, and you're just in one area, your goal is to push your programs to the end, even if it's not going to work, ok? And so, countering this kind of incentive is, is, is very important to be successful, because you want to fail fast and…”
Jerome Pesenti Oct 26, 2017 ▶ 20:25 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Disclosure
BenevolentAI cannot discover unstudied targets; it only repurposes existing knowledge
“We don't come up with new targets that have never been looked at. For example, the system by definition cannot do that. So it's always about repurposing some existing knowledge.”
Jerome Pesenti Oct 26, 2017 ▶ 25:54 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Assertion Supported
Pesenti: Facebook uses embedding algorithms to automatically match misleading content
“And then when they fly content that should be at least, you know, shown as a misleading, then we have this very advanced similarity algorithm that kind of like look at an embedding of the of the content itself. Again, it can be the image itself or a multimodal…”
Jerome Pesenti Jun 10, 2020 ▶ 10:35 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
Pesenti: Facebook gained a year of usage growth in one month
“Basically the growth that happened in, just a matter of a month was what we predicted would happen over more than a year”
Jerome Pesenti Jun 10, 2020 ▶ 17:03 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
Pesenti: Alexa and Google Home rely on limited, scripted dialogues
“When you interact with something like Alexa or Google Home today, right, this system basically do intent recognition and then they have a very scripted dialogue after this, right? So usually You recognize one of the steps, and it's very limited because you can…”
Jerome Pesenti Jun 10, 2020 ▶ 28:37 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Prediction Not checkable as stated
Pesenti: AI-assisted scientific discovery will break through in coming years
“I do think that AI-assisted science is, has a huge future ahead of us, you know, that it's chemistry, biology, physics leveraging AI system to make better discovery is something that's gonna really break through in the coming years.”
Jerome Pesenti Jun 10, 2020 ▶ 40:24 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Insight
Pesenti: Do not train production AI chatbots on Reddit data
“So I would not advise to train a production bot on Reddit.”
Jerome Pesenti Jun 10, 2020 ▶ 44:31 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Supported
Drug discovery return on investment is exponentially decreasing
“The return on investment for drug discovery is exponentially decreasing.”
Jerome Pesenti Oct 26, 2017 ▶ 0:37 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Insight
Weak supervision is the sweet spot for early-stage AI startups
“The sweet spot these days is what we call weak supervision or semi supervision for startup.”
Jerome Pesenti Oct 26, 2017 ▶ 8:34 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Disclosure
BenevolentAI is exploring applying its AI platform to battery technology
“And our vision is that if we can do that for drugs, we may do that also for materials. We are actually looking at battery technology.”
Jerome Pesenti Oct 26, 2017 ▶ 18:21 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Assertion Not checkable as stated
Pesenti: Facebook has more ML engineers outside core AI team than inside
“And actually there are more ML engineers outside my team than within.”
Jerome Pesenti Jun 10, 2020 ▶ 2:54 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
Pesenti: FAIR lab had about 300 researchers across eight offices in 2020
“We don't share, but you're yes. Bullpark is good. Yeah.”
Jerome Pesenti Jun 10, 2020 ▶ 3:20 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Supported
Pesenti: Facebook trains single XLM-R models across 100 languages simultaneously
“We try to learn a hundred languages at the same time in a single model using transformer architecture”
Jerome Pesenti Jun 10, 2020 ▶ 6:51 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Disclosure
Pesenti: Facebook is not an AI vendor and has no cloud offering
“So for us, actually, we're not selling AI. We're not a vendor. We don't have a cloud offering.”
Jerome Pesenti Jun 10, 2020 ▶ 22:56 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Not checkable as stated
Pesenti: Facebook has as many data scientists as product managers
“So actually, you know, to get an idea, there are as many data scientists in Facebook as they are product managers, right?”
Jerome Pesenti Jun 10, 2020 ▶ 42:56 Fireside Chat: Jerome Pesenti (Head of AI, Facebook) with Matt Turck (Partner, FirstMark)
Assertion Supported
Up to 10,000 bioscience papers are published every day
“There's like a few thousand to like 10,000 papers that are written every day, ah, in bioscience”
Jerome Pesenti Oct 26, 2017 ▶ 1:38 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Assertion Partly supported
There are 90 million patents and 30 million scientific articles available
“There's ninety million full-text patents, thirty million scientific article”
Jerome Pesenti Oct 26, 2017 ▶ 2:12 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
Assertion Not checkable as stated
BenevolentAI's biological knowledge graph contains approximately one billion facts
“Think of it as like a billion facts, ok?”
Jerome Pesenti Oct 26, 2017 ▶ 7:27 Using AI to Accelerate Drug Discovery // Jerome Pesenti, BenevolentAI (FirstMark's Data Driven)
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