The Ledger
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why aren't all 4 resolved? a statement only gets an assessment when the public record can support or contradict it. opinions and what-ifs never can, and 0 checkable ones are still open, waiting for their date. predictions held up or didn't; assertions are supported or contradicted. on every card: ▮▮▮▮▮ certainty · ▮▮▮▮▮ debate potential. speakers are clickable
Interpreting novel genetic variants costs 100x to 1000x more than sequencing
“And interpreting each one of those under the current clinical practices costs 50 to a hundred dollars. So we're talking about a hundred to thousand-fold increase in the cost of interpretation relative to the cost of data acquisition.”
Only 0.6% of disease-associated gene mutations have clinical interpretations
“If we look across all of the disease-associated genes that we know today, we only have clinical interpretations for roughly . Six percent of the possible mutations in them.”