Koki Hirasaki, an expert on the Andreessen Horowitz bio team, explains the shift in biotech partnering models over the past decade toward building standalone commercial entities.
“What we've seen really over the last 10 years is a lot of boards want the companies to be able to be standalone. And so, what you see are, in this fairly typical and actually Spark is a good example, where the company will keep commercial rights for the U.S. And, you know out-license ex-U.S. Rights.”
quote is from the automated transcript, cleaned for reading:
filler sounds and stutters are removed, nothing is rephrased. names can be misheard
(the analysis reads context, assessments check outside sources). how →
More from Koki Hirasaki
AssertionSupported
Hirasaki: Immuno-Oncology Acquisitions Occurred Before Human Clinical Data
“Now, there are some areas of clear exception. So, so very competitive hot areas like oncology, immuno-oncology over the last few years. You've seen this shift in acquisitions earlier on. In, in phase one, and actually even earlier just because it was so compet…”
Koki HirasakiFeb 28, 2019▶ 13:28What’s with All the Bio M&A in 2019?: A Quick Take
“And then with the Spark acquisition same thing BMS, I'm sorry Roche was a laggard in the space, and now suddenly leaped ahead with not only a marketed gene therapy, but this AAV platform that it could use for delivering other gene therapies.”
Koki HirasakiFeb 28, 2019▶ 5:59What’s with All the Bio M&A in 2019?: A Quick Take
Insight
Hirasaki: Pharma Companies Wait for Phase 2a Data Before Doubling Down
“So, so, you know, it's typical to You know, see pharma companies wait for proof of concept, you know, phase IIa data that shows safety and some efficacy before doubling down.”
Koki HirasakiFeb 28, 2019▶ 13:14What’s with All the Bio M&A in 2019?: A Quick Take
Insight
Hirasaki: Top Corporate Buyers Fly In Executive Committees for Priority Biotech Deals
“I can tell you that big companies that really want an asset, that really want to show commitment to that program, will fly, you know, a big portion of their executive committee out in final negotiations to say, hey we're committed.”
Koki HirasakiFeb 28, 2019▶ 17:55What’s with All the Bio M&A in 2019?: A Quick Take
Insight
Pharma Demands Manufacturing Control Unless Assets Require Specialized Know-How
“If the asset is very critical to the business the pharma company will In all likelihood, want to control the manufacturing and distribution unless it is a very niche specialized product like gene therapies and AAVs, which require specialized know-how.”
Koki HirasakiFeb 28, 2019▶ 20:33What’s with All the Bio M&A in 2019?: A Quick Take
AssertionPartly supported
Hirasaki: Major biopharma companies faced critical patent cliffs in 2018
“Roche lost exclusivity on Zolaire and Rituxin. Pfizer lost exclusivity on Lyrica. And GSK lost exclusivity on Advair.”
Koki HirasakiFeb 28, 2019▶ 1:30What’s with All the Bio M&A in 2019?: A Quick Take
Made with StarZero
Turn any episode into a week of clips.
This entire site, over 1,000 episodes transcribed, diarized, checked and made playable,
runs on the StarZero media pipeline. Drop in your own episode and the podcast clipper finds the
moments worth sharing, cuts them, captions them, and reframes them for every feed.
We use essential cookies to make the site work. With your permission we
also use analytics cookies (Google Analytics and Mixpanel) to understand
usage and improve StarZero. See our Cookie Policy.