“Illumina effectively is a monopoly in the space of DNA sequencing, and in a lot of ways, rightly so.”
quote is from the automated transcript, cleaned for reading:
filler sounds and stutters are removed, nothing is rephrased. names can be misheard
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More from Gabriel Ott
Opinion
Otte: Insurance payers and clinicians are blocking diagnostic innovation
“It's really the payers and some of the clinicians that are being the inhibitors to this progress.”
Gabriel OttJan 2, 2019▶ 12:51a16z Podcast | When Will Genomics Live Up to the Hype?
PredictionNot checkable as stated
Ott: Dynamic DNA testing will enable detection of any disease with immune changes
“The underlying biology should theoretically enable us to detect any diseases where there is an immune change.”
Gabriel OttJan 2, 2019▶ 9:18a16z Podcast | Revisiting the Gene
AssertionPartly supported
Ott: Mammography Screenings Have a 50% False Positive Rate
“Breast cancer, and specifically mammography as a screening method, has a false positive rate of 50%.”
Gabriel OttJan 2, 2019▶ 11:30a16z Podcast | Revisiting the Gene
AssertionPartly supported
Otte: PSA tests and mammograms have false positive rates up to 75%
“In the field of cancer screening, cancer diagnostics, we're used to, like, really, really bad tests. So like PSA for prostate cancer detection, mammography for breast cancer detection, these things have false positive rates of anywhere from, ah, 50 to 75%.”
Gabriel OttJan 2, 2019▶ 11:24a16z Podcast | When Will Genomics Live Up to the Hype?
Opinion
Ott: Single-gene targeted approaches fail for early cancer detection
“What sometimes happens when you are very focused though, is you missed a bigger picture. And what we're realizing is with respect to things like detecting cancer early, that focused approach is not working.”
Gabriel OttJan 2, 2019▶ 9:49a16z Podcast | On the Genomics of Disease, From Science to Business
Disclosure
Freenome detects dynamic cell-free DNA from circulating immune cells
“What we're detecting is DNA fragments that are actually coming from the immune cells that are turning over in your body.”
Gabriel OttJan 2, 2019▶ 8:39a16z Podcast | Revisiting the Gene
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