Lada Nuzhna, biotech investor, discusses why novel platforms like gene editors face commercial resistance when competing against existing standard therapies.
“So I think many new modalities will be bottlenecked by the Beatles, better than the Beatles problem.”
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More from Lada Nuzhna
AssertionNot checkable as stated
Nuzhna: China leads global development in in vivo CAR-T and gene editing
“They are now leading in, in VivoC RTs, they are leading in gene editing and gene therapy, and partially due to this ability to do those investigator-initiated trials.”
Lada NuzhnaNov 14, 2025▶ 17:09The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
PredictionNot checkable as stated
Nuzhna: AI will solve open biology questions before predicting drug efficacy
“Many big bio problems and open questions will be solved with AI way before we can predict efficacy for drugs.”
Lada NuzhnaNov 14, 2025▶ 25:23The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
PredictionNot checkable as stated
Nuzhna: AI virtual cell models are near realization with existing data
“Virtual cells is actually not that far out. I think we have all the necessary data to generate something like that.”
Lada NuzhnaNov 14, 2025▶ 25:33The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
Insight
Nuzhna: US multi-payer insurance system disincentivizes early preventive healthcare
“The payer that pays the most for diseases of aged population is Medicare which kicks in after 65. Before then we have a multi-payer system where patients Tend to rotate their insurance every few years. And so there's really not much incentive for someone to co…”
Lada NuzhnaNov 14, 2025▶ 34:49The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
PredictionNot checkable as stated
Nuzhna: Medicine will treat aging before understanding its underlying mechanisms
“I think we would be able to treat aging before we understand how to measure it or what it is or why it happens.”
Lada NuzhnaNov 14, 2025▶ 40:24The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
AssertionNot checkable as stated
Nuzhna: Modern medical stack can eliminate heart attacks for current generation
“And it does seem like we kind of hit a point where actually like our generation shouldn't die of heart attacks. It seems like we have everything to prevent high cholesterol in people from, like you can take antibodies sRNAs, small molecules, sun gene editors. …”
Lada NuzhnaNov 14, 2025▶ 41:45The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
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