Kristen Fortney is the CEO of BioAge, a biotech startup developing therapies for biological aging. She presents proprietary genomic data showing a blood protein target correlated with healthspan.
“One of the targets we're working on now is a protein that circulates in your blood, and we discovered that humans who have higher levels of this protein live longer, are less frail, and are protected from disease.”
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More from Kristen Fortney
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Fortney: Near-term therapies will add 10 to 20 years to human life
“I think the near-term therapies are going to add, say, 10 to 20 years.”
Kristen FortneyJan 2, 2019▶ 28:05a16z Podcast | The Science Of Extending Life
What-if
Targeting aging directly could extend average human lifespan to 113 years
“That would get the average lifespan up to 113 by targeting aging directly rather than targeting individual diseases one at a time. And what's really key too is this would be an additional 30 years of healthy life.”
Current longevity clinical trials could add 10 to 20 healthy years
“Three different therapies are already in the clinic today. So as I mentioned, there are drugs targeting senescence, metformin, and there are drugs targeting rapamycin being tested in clinical trials now. And I think that could already add 10 to 20 years of hea…”
Kristen Fortney argues there is no hard biological limit on lifespan
“Going forward in the future, I think it's a really important point to mention that there is no hard biological limit on how long we can live, and these are a couple really fascinating examples. Bowhead whales, their average lifespan is over 200 years, so they'…”
Fortney: Clearing senescent cells in mice boosted lifespan by 30 percent
“And they showed that if you killed senescent cells in a mouse, you could boost lifespan by 30%.”
Kristen FortneyJan 2, 2019▶ 9:24a16z Podcast | The Science Of Extending Life
AssertionSupported
Fortney: NIA tested 30 lifespan drugs compared to 110,000 for cancer
“The National Cancer Institute, the total number of drugs they've given to mice to see if they cure mouse cancer is over a 110,000. The number of drugs that the National Institute on Aging has given to mice to see if they live longer is 30.”
Kristen FortneyJan 2, 2019▶ 13:21a16z Podcast | The Science Of Extending Life
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