The Ledger

Every statement that passed quotation and attribution checks. Mix any filter with any other: certainty 1/5, debate potential 5/5, or both at once.

clear all ✕

why aren't all 11 resolved? a statement only gets an assessment when the public record can support or contradict it. opinions and what-ifs never can, and 0 checkable ones are still open, waiting for their date. predictions held up or didn't; assertions are supported or contradicted. on every card: ▮▮▮▮▮ certainty · ▮▮▮▮▮ debate potential. speakers are clickable

Assertion Not checkable as stated
Wickramasekara: Clunky enterprise systems force pharma scientists to email sensitive IP
“A lot of these companies, they do have systems that exist, but they're quite clunky and not integrated. So the scientists resort to using email, and this is whatever email systems they have set up. Sometimes they're personal gmails as well.”
Sajith Wickramasekara Feb 3, 2017 ▶ 15:37 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Assertion Not checkable as stated
Wickramasekara: Advanced drug development lacks modern software and data infrastructure
“You would think that such deliberate advanced science would have a large amount of software and advanced data behind it as well, but that's actually not the case.”
Sajith Wickramasekara Feb 3, 2017 ▶ 2:24 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Insight
Wickramasekara: Curing cancer with Excel is worse than dev without version control
“They're literally trying to cure cancer using Excel. This is the equivalent of one of the companies you work at building software without version control. It's honestly probably a little worse, actually.”
Sajith Wickramasekara Feb 3, 2017 ▶ 6:01 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Insight
Wickramasekara: Applying standard data practices to life sciences requires little domain expertise
“Using quite standard data practices we were able to make a big dent in a really high impact field that touches everyone and it doesn't require a ton of domain expertise.”
Sajith Wickramasekara Feb 3, 2017 ▶ 12:51 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Assertion Not checkable as stated
Wickramasekara: Life science research still runs on paper, email, and Excel
“This is an industry that runs on paper, email, and Excel, and it's something that touches everyone.”
Sajith Wickramasekara Feb 3, 2017 ▶ 3:28 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Insight
Wickramasekara: Antibody drug discovery has no fixed deterministic formula
“For most antibody research. The discovery process itself is a work in process. There's no formula for spitting out a drug by going through some set of steps that's going to work.”
Sajith Wickramasekara Feb 3, 2017 ▶ 9:39 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Insight
Wickramasekara: Scientific research can largely be broken down into processes
“Science can sometimes seem like an art, and it is to some degree, but a lot of it can be broken down into a process.”
Sajith Wickramasekara Feb 3, 2017 ▶ 10:44 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Assertion Not checkable as stated
Wickramasekara: Most Benchling employees have no background in life science
“Most of our team actually has no background in the live science at all.”
Sajith Wickramasekara Feb 3, 2017 ▶ 13:05 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Disclosure
Wickramasekara: Benchling adoption spread bottom-up from grad school to pharma giants
“It started with the younger folks. It started with folks in grad school who are going to adopt a tool out of their own volition just because it makes their lives better, and you go to the small biotechs, medium biotechs, and eventually the large companies, the…”
Sajith Wickramasekara Feb 3, 2017 ▶ 14:25 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Assertion Not checkable as stated
Wickramasekara: Expiring patents and cost pressures force pharma to adopt cloud
“The pharma industry's typically been wildly profitable, and it still is, but it's under cost pressure for the first time just because of patents expiring and that sort of thing, and therefore they're, as a result of economics, becoming more amenable to cloud s…”
Sajith Wickramasekara Feb 3, 2017 ▶ 16:51 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
Assertion Partly supported
Wickramasekara: Antibody drug discovery begins with tens of thousands of candidates
“Creating something like Avastin actually involves starting with tens of thousands of candidate antibodies in the beginning.”
Sajith Wickramasekara Feb 3, 2017 ▶ 4:04 Drug Discovery as a Data Problem // Sajith Wickramasekara, Benchling (FirstMark's Data Driven)
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